4keh: Difference between revisions
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{{STRUCTURE_4keh| PDB=4keh | SCENE= }} | |||
===Crosslinked Crystal Structure of Type II Fatty Synthase Dehydratase, FabA, and Acyl Carrier Protein, AcpP=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/FABA_ECOLI FABA_ECOLI]] Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. Is inactive in the dehydration of long chain unsaturated beta-hydroxyacyl-ACP.<ref>PMID:8910376</ref> [[http://www.uniprot.org/uniprot/K0BL73_ECO1E K0BL73_ECO1E]] Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity).[RuleBase:RU003545][HAMAP-Rule:MF_01217] | |||
==About this Structure== | |||
[[4keh]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KEH OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Burkart, M.]] | |||
[[Category: Finzel, K.]] | |||
[[Category: Haushalter, R.]] | |||
[[Category: Le, B C.]] | |||
[[Category: Leong, J.]] | |||
[[Category: Nguyen, C.]] | |||
[[Category: Tsai, S C.]] | |||
[[Category: Acyl carrier protein]] | |||
[[Category: Dehydratase/isomerase]] | |||
[[Category: Fatty acid synthesis]] | |||
[[Category: Isomerase-biosynthetic protein complex]] | |||
[[Category: Protein-protein complex]] | |||