2g65: Difference between revisions

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[[Image:2g65.jpg|left|200px]]<br /><applet load="2g65" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2g65.jpg|left|200px]]
caption="2g65, resolution 2.30&Aring;" />
 
'''Crystal Structure of X. campestris N-acetylornithine transcarbamoylase E92A mutant complexed with carbamoyl phosphate and N-succinylnorvaline'''<br />
{{Structure
|PDB= 2g65 |SIZE=350|CAPTION= <scene name='initialview01'>2g65</scene>, resolution 2.30&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=SN0:N-(3-CARBOXYPROPANOYL)-L-NORVALINE'>SN0</scene> and <scene name='pdbligand=CP:PHOSPHORIC ACID MONO(FORMAMIDE)ESTER'>CP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/N-acetylornithine_carbamoyltransferase N-acetylornithine carbamoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.3.9 2.1.3.9]
|GENE= argF' ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=340 Xanthomonas campestris pv. campestris])
}}
 
'''Crystal Structure of X. campestris N-acetylornithine transcarbamoylase E92A mutant complexed with carbamoyl phosphate and N-succinylnorvaline'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2G65 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Xanthomonas_campestris_pv._campestris Xanthomonas campestris pv. campestris] with <scene name='pdbligand=SO4:'>SO4</scene>, <scene name='pdbligand=SN0:'>SN0</scene> and <scene name='pdbligand=CP:'>CP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/N-acetylornithine_carbamoyltransferase N-acetylornithine carbamoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.3.9 2.1.3.9] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G65 OCA].  
2G65 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Xanthomonas_campestris_pv._campestris Xanthomonas campestris pv. campestris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G65 OCA].  


==Reference==
==Reference==
A single mutation in the active site swaps the substrate specificity of N-acetyl-L-ornithine transcarbamylase and N-succinyl-L-ornithine transcarbamylase., Shi D, Yu X, Cabrera-Luque J, Chen TY, Roth L, Morizono H, Allewell NM, Tuchman M, Protein Sci. 2007 Aug;16(8):1689-99. Epub 2007 Jun 28. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17600144 17600144]
A single mutation in the active site swaps the substrate specificity of N-acetyl-L-ornithine transcarbamylase and N-succinyl-L-ornithine transcarbamylase., Shi D, Yu X, Cabrera-Luque J, Chen TY, Roth L, Morizono H, Allewell NM, Tuchman M, Protein Sci. 2007 Aug;16(8):1689-99. Epub 2007 Jun 28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17600144 17600144]
[[Category: N-acetylornithine carbamoyltransferase]]
[[Category: N-acetylornithine carbamoyltransferase]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: transferase]]
[[Category: transferase]]


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