4kg8: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4kg8|  PDB=4kg8  |  SCENE=  }}
===Crystal structure of light mutant===


The entry 4kg8 is ON HOLD
==Function==
[[http://www.uniprot.org/uniprot/TNF14_HUMAN TNF14_HUMAN]] Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.


Authors: Liu, W., Zhan, C., Rajesh, P., Bonanno, J.B., Nathenson, S.G., Almo, S.C., New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN)
==About this Structure==
 
[[4kg8]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KG8 OCA].  
Description: Crystal structure of light mutant
[[Category: Homo sapiens]]
[[Category: Almo, S C.]]
[[Category: Bonanno, J B.]]
[[Category: IFN, Atoms-to-Animals:.The Immune Function Network.]]
[[Category: Liu, W.]]
[[Category: NYSGRC, New York Structural Genomics Research Consortium.]]
[[Category: Nathenson, S G.]]
[[Category: Rajesh, P.]]
[[Category: Zhan, C.]]
[[Category: Atoms-to-animals: the immune function network]]
[[Category: Bind tnf receptor hvem and ltbr]]
[[Category: Cytokine]]
[[Category: Dcr3]]
[[Category: Hvem]]
[[Category: Ifn]]
[[Category: Immunity]]
[[Category: Jelly-roll fold]]
[[Category: Ltbr]]
[[Category: Membrane]]
[[Category: N-glycosylation]]
[[Category: New york structural genomics research consortium]]
[[Category: Nysgrc]]
[[Category: Protein structure initiative]]
[[Category: Psi-biology]]
[[Category: Secreted protein]]
[[Category: Structural genomic]]
[[Category: Tnf superfamily]]

Revision as of 21:03, 7 August 2013

Template:STRUCTURE 4kg8

Crystal structure of light mutant

Function

[TNF14_HUMAN] Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus.

About this Structure

4kg8 is a 3 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

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