2gbg: Difference between revisions

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[[Image:2gbg.gif|left|200px]]<br /><applet load="2gbg" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2gbg.gif|left|200px]]
caption="2gbg, resolution 3.000&Aring;" />
 
'''rat DPP-IV with alkynyl cyanopyrrolidine #2'''<br />
{{Structure
|PDB= 2gbg |SIZE=350|CAPTION= <scene name='initialview01'>2gbg</scene>, resolution 3.000&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=1AD:(1S)-2-[(2S,5R)-2-(AMINOMETHYL)-5-PROP-1-YN-1-YLPYRROLIDIN-1-YL]-1-CYCLOPENTYL-2-OXOETHANAMINE'>1AD</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Dipeptidyl-peptidase_IV Dipeptidyl-peptidase IV], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.14.5 3.4.14.5]
|GENE=
}}
 
'''rat DPP-IV with alkynyl cyanopyrrolidine #2'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2GBG is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=1AD:'>1AD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Dipeptidyl-peptidase_IV Dipeptidyl-peptidase IV], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.14.5 3.4.14.5] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GBG OCA].  
2GBG is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GBG OCA].  


==Reference==
==Reference==
Crystal structures of DPP-IV (CD26) from rat kidney exhibit flexible accommodation of peptidase-selective inhibitors., Longenecker KL, Stewart KD, Madar DJ, Jakob CG, Fry EH, Wilk S, Lin CW, Ballaron SJ, Stashko MA, Lubben TH, Yong H, Pireh D, Pei Z, Basha F, Wiedeman PE, von Geldern TW, Trevillyan JM, Stoll VS, Biochemistry. 2006 Jun 20;45(24):7474-82. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16768443 16768443]
Crystal structures of DPP-IV (CD26) from rat kidney exhibit flexible accommodation of peptidase-selective inhibitors., Longenecker KL, Stewart KD, Madar DJ, Jakob CG, Fry EH, Wilk S, Lin CW, Ballaron SJ, Stashko MA, Lubben TH, Yong H, Pireh D, Pei Z, Basha F, Wiedeman PE, von Geldern TW, Trevillyan JM, Stoll VS, Biochemistry. 2006 Jun 20;45(24):7474-82. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16768443 16768443]
[[Category: Dipeptidyl-peptidase IV]]
[[Category: Dipeptidyl-peptidase IV]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
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[[Category: serine peptidase beta propeller]]
[[Category: serine peptidase beta propeller]]


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