2gcq: Difference between revisions

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[[Image:2gcq.jpg|left|200px]]<br /><applet load="2gcq" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2gcq.jpg|left|200px]]
caption="2gcq, resolution 2.0&Aring;" />
 
'''Fully ligated E.Coli Adenylosuccinate Synthetase with GTP, 2'-deoxy-IMP and Hadacidin'''<br />
{{Structure
|PDB= 2gcq |SIZE=350|CAPTION= <scene name='initialview01'>2gcq</scene>, resolution 2.0&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=DOI:9-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-6-(PHOSPHONOOXY)-9H-PURINE'>DOI</scene>, <scene name='pdbligand=GDP:GUANOSINE-5'-DIPHOSPHATE'>GDP</scene> and <scene name='pdbligand=HAD:(CARBOXYHYDROXYAMINO)ETHANOIC ACID'>HAD</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Adenylosuccinate_synthase Adenylosuccinate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.4 6.3.4.4]
|GENE= purA, adeK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
}}
 
'''Fully ligated E.Coli Adenylosuccinate Synthetase with GTP, 2'-deoxy-IMP and Hadacidin'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2GCQ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=DOI:'>DOI</scene>, <scene name='pdbligand=GDP:'>GDP</scene> and <scene name='pdbligand=HAD:'>HAD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Adenylosuccinate_synthase Adenylosuccinate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.4 6.3.4.4] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GCQ OCA].  
2GCQ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GCQ OCA].  


==Reference==
==Reference==
Cavitation as a mechanism of substrate discrimination by adenylosuccinate synthetases., Iancu CV, Zhou Y, Borza T, Fromm HJ, Honzatko RB, Biochemistry. 2006 Sep 26;45(38):11703-11. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16981730 16981730]
Cavitation as a mechanism of substrate discrimination by adenylosuccinate synthetases., Iancu CV, Zhou Y, Borza T, Fromm HJ, Honzatko RB, Biochemistry. 2006 Sep 26;45(38):11703-11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16981730 16981730]
[[Category: Adenylosuccinate synthase]]
[[Category: Adenylosuccinate synthase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: adenylosuccinate synthetase; adss; gtp; hadacidin; 2'-deoxy-imp]]
[[Category: adenylosuccinate synthetase; adss; gtp; hadacidin; 2'-deoxy-imp]]


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