3qve: Difference between revisions

Line 1:

~~{{STRUCTURE_3qve| PDB=3qve | SCENE= }}~~

==Crystal structure of human HMG box-containing protein 1, HBP1==

===Crystal structure of human HMG box-containing protein 1, HBP1===

== Structural highlights ==

==~~Function~~==

<table><tr><td colspan='2'>[[3qve]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QVE OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QVE FirstGlance].

[[~~http://www.uniprot.org/uniprot/HBP1_HUMAN HBP1_HUMAN~~]] ~~Transcriptional repressor that binds to the promoter region of target genes~~. ~~Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5~~'~~-TTCATTCATTCA-3~~'~~. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.<ref~~>~~PMID:10958660~~<~~/ref~~> <~~ref~~>~~PMID:10562551~~<~~/ref> <ref>PMID:11500377</ref~~>

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>

<tr id='gene'><td class="sblockLbl">[[Gene|Gene:]]</td><td class="sblockDat">HBP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>

~~==About this Structure==~~

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qve FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qve OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qve RCSB], [http://www.ebi.ac.uk/pdbsum/3qve PDBsum]</td></tr>

[[3qve]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QVE OCA].

</table>

__TOC__

==~~Reference~~==

</StructureSection>

<~~references group~~="~~xtra~~"/><~~references~~/>

[[Category: Homo sapiens]]

[[Category: Arrowsmith, C H.]]

[[Category: Arrowsmith, C H]]

[[Category: Bountra, C.]]

[[Category: Bountra, C]]

[[Category: Chaikuad, A.]]

[[Category: Chaikuad, A]]

[[Category: Cocking, R.]]

[[Category: Cocking, R]]

[[Category: ~~Consortium,~~ Structural ~~Genomics.~~]]

[[Category: Structural genomic]]

[[Category: Delft, F von.]]

[[Category: Delft, F von]]

[[Category: Edwards, A M.]]

[[Category: Edwards, A M]]

[[Category: Filippakopoulos, P.]]

[[Category: Filippakopoulos, P]]

[[Category: Krojer, T.]]

[[Category: Krojer, T]]

[[Category: Krysztofinska, E.]]

[[Category: Krysztofinska, E]]

[[Category: Oppermann, U.]]

[[Category: Oppermann, U]]

[[Category: Ugochukwu, E.]]

[[Category: Ugochukwu, E]]

[[Category: Vollmar, M.]]

[[Category: Vollmar, M]]

[[Category: Weigelt, J.]]

[[Category: Weigelt, J]]

[[Category: Yue, W W.]]

[[Category: Yue, W W]]

[[Category: Axh domain]]

[[Category: Hbp1]]

[[Category: Hmg box transcription factor 1]]

[[Category: Sgc]]

~~[[Category: Structural genomics consortium]]~~

[[Category: Transcription]]

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@@ Line 1: / Line 1: @@
-{{STRUCTURE_3qve|  PDB=3qve  |  SCENE=  }}
+==Crystal structure of human HMG box-containing protein 1, HBP1==
-===Crystal structure of human HMG box-containing protein 1, HBP1===
+<StructureSection load='3qve' size='340' side='right' caption='[[3qve]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
+== Structural highlights ==
-==Function==
+<table><tr><td colspan='2'>[[3qve]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QVE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3QVE FirstGlance]. <br>
-[[http://www.uniprot.org/uniprot/HBP1_HUMAN HBP1_HUMAN]] Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.<ref>PMID:10958660</ref> <ref>PMID:10562551</ref> <ref>PMID:11500377</ref>
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HBP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr>
-==About this Structure==
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3qve FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qve OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3qve RCSB], [http://www.ebi.ac.uk/pdbsum/3qve PDBsum]</span></td></tr>
-[[3qve]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QVE OCA].
+</table>
+__TOC__
-==Reference==
+</StructureSection>
-<references group="xtra"/><references/>
 [[Category: Homo sapiens]]
-[[Category: Arrowsmith, C H.]]
+[[Category: Arrowsmith, C H]]
-[[Category: Bountra, C.]]
+[[Category: Bountra, C]]
-[[Category: Chaikuad, A.]]
+[[Category: Chaikuad, A]]
-[[Category: Cocking, R.]]
+[[Category: Cocking, R]]
-[[Category: Consortium, Structural Genomics.]]
+[[Category: Structural genomic]]
-[[Category: Delft, F von.]]
+[[Category: Delft, F von]]
-[[Category: Edwards, A M.]]
+[[Category: Edwards, A M]]
-[[Category: Filippakopoulos, P.]]
+[[Category: Filippakopoulos, P]]
-[[Category: Krojer, T.]]
+[[Category: Krojer, T]]
-[[Category: Krysztofinska, E.]]
+[[Category: Krysztofinska, E]]
-[[Category: Oppermann, U.]]
+[[Category: Oppermann, U]]
-[[Category: Ugochukwu, E.]]
+[[Category: Ugochukwu, E]]
-[[Category: Vollmar, M.]]
+[[Category: Vollmar, M]]
-[[Category: Weigelt, J.]]
+[[Category: Weigelt, J]]
-[[Category: Yue, W W.]]
+[[Category: Yue, W W]]
 [[Category: Axh domain]]
 [[Category: Hbp1]]
 [[Category: Hmg box transcription factor 1]]
 [[Category: Sgc]]
-[[Category: Structural genomics consortium]]
 [[Category: Transcription]]