3pva: Difference between revisions
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Revision as of 08:36, 8 May 2013
PENICILLIN V ACYLASE FROM B. SPHAERICUS
Function
[PAC_BACSH] The enzyme catalyzes the conversion of penicillin to 6-aminopenicillanate The precursor, furthermore, acts as a self-processing peptidase that cleaves off the propeptide. All peptidase activity is lost on conversion to the mature peptidase.
About this Structure
3pva is a 8 chain structure with sequence from Lysinibacillus sphaericus. Full crystallographic information is available from OCA.
See Also
Reference
- Suresh CG, Pundle AV, SivaRaman H, Rao KN, Brannigan JA, McVey CE, Verma CS, Dauter Z, Dodson EJ, Dodson GG. Penicillin V acylase crystal structure reveals new Ntn-hydrolase family members. Nat Struct Biol. 1999 May;6(5):414-6. PMID:10331865 doi:10.1038/8213
