3pva: Difference between revisions

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{{STRUCTURE_3pva|  PDB=3pva  |  SCENE=  }}
==PENICILLIN V ACYLASE FROM B. SPHAERICUS==
===PENICILLIN V ACYLASE FROM B. SPHAERICUS===
<StructureSection load='3pva' size='340' side='right' caption='[[3pva]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
 
== Structural highlights ==
==Function==
<table><tr><td colspan='2'>[[3pva]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PVA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3PVA FirstGlance]. <br>
[[http://www.uniprot.org/uniprot/PAC_BACSH PAC_BACSH]] The enzyme catalyzes the conversion of penicillin to 6-aminopenicillanate The precursor, furthermore, acts as a self-processing peptidase that cleaves off the propeptide. All peptidase activity is lost on conversion to the mature peptidase.
</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Penicillin_amidase Penicillin amidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.1.11 3.5.1.11] </span></td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3pva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3pva OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3pva RCSB], [http://www.ebi.ac.uk/pdbsum/3pva PDBsum]</span></td></tr>
==About this Structure==
</table>
[[3pva]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Lysinibacillus_sphaericus Lysinibacillus sphaericus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3PVA OCA].  
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pv/3pva_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Penicillin acylase|Penicillin acylase]]
*[[Penicillin acylase|Penicillin acylase]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:010331865</ref><references group="xtra"/><references/>
[[Category: Lysinibacillus sphaericus]]
[[Category: Lysinibacillus sphaericus]]
[[Category: Penicillin amidase]]
[[Category: Penicillin amidase]]
[[Category: Brannigan, J A.]]
[[Category: Brannigan, J A]]
[[Category: Dauter, Z.]]
[[Category: Dauter, Z]]
[[Category: Dodson, E J.]]
[[Category: Dodson, E J]]
[[Category: Dodson, G G.]]
[[Category: Dodson, G G]]
[[Category: Mcvey, C E.]]
[[Category: Mcvey, C E]]
[[Category: Pundle, A V.]]
[[Category: Pundle, A V]]
[[Category: Rao, K N.]]
[[Category: Rao, K N]]
[[Category: Sivaraman, H.]]
[[Category: Sivaraman, H]]
[[Category: Suresh, C G.]]
[[Category: Suresh, C G]]
[[Category: Verma, C S.]]
[[Category: Verma, C S]]
[[Category: Amidohydrolase]]
[[Category: Amidohydrolase]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
[[Category: Ntn hydrolase]]
[[Category: Ntn hydrolase]]
[[Category: Penicillin v acylase]]
[[Category: Penicillin v acylase]]