2gie: Difference between revisions

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[[Image:2gie.gif|left|200px]]<br /><applet load="2gie" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2gie.gif|left|200px]]
caption="2gie, resolution 2.6&Aring;" />
 
'''HincII bound to cognate DNA GTTAAC'''<br />
{{Structure
|PDB= 2gie |SIZE=350|CAPTION= <scene name='initialview01'>2gie</scene>, resolution 2.6&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NA:SODIUM ION'>NA</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Type_II_site-specific_deoxyribonuclease Type II site-specific deoxyribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.4 3.1.21.4]
|GENE= hincIIR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=727 Haemophilus influenzae])
}}
 
'''HincII bound to cognate DNA GTTAAC'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2GIE is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae] with <scene name='pdbligand=NA:'>NA</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Type_II_site-specific_deoxyribonuclease Type II site-specific deoxyribonuclease], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.21.4 3.1.21.4] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GIE OCA].  
2GIE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Haemophilus_influenzae Haemophilus influenzae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GIE OCA].  


==Reference==
==Reference==
Alteration of sequence specificity of the type II restriction endonuclease HincII through an indirect readout mechanism., Joshi HK, Etzkorn C, Chatwell L, Bitinaite J, Horton NC, J Biol Chem. 2006 Aug 18;281(33):23852-69. Epub 2006 May 4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16675462 16675462]
Alteration of sequence specificity of the type II restriction endonuclease HincII through an indirect readout mechanism., Joshi HK, Etzkorn C, Chatwell L, Bitinaite J, Horton NC, J Biol Chem. 2006 Aug 18;281(33):23852-69. Epub 2006 May 4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16675462 16675462]
[[Category: Haemophilus influenzae]]
[[Category: Haemophilus influenzae]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: protein dna complex]]
[[Category: protein dna complex]]


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