2gk1: Difference between revisions

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[[Image:2gk1.gif|left|200px]]~~<br /><applet load~~="2gk1~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~

[[Image:2gk1.gif|left|200px]]

~~caption="~~2gk1, resolution 3.25Å" />

'''X-ray crystal structure of NGT-bound HexA'''~~<br />~~

{{Structure

|PDB= 2gk1 |SIZE=350|CAPTION= <scene name='initialview01'>2gk1</scene>, resolution 3.25Å

|SITE=

|LIGAND= <scene name='pdbligand=NGT:3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL'>NGT</scene>

|ACTIVITY= [http://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52]

|GENE=

}}

'''X-ray crystal structure of NGT-bound HexA'''

==Overview==

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==About this Structure==

2GK1 is a [~~http://en.wikipedia.org/wiki/Protein_complex~~ Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] ~~with <scene name='pdbligand=NGT:'>NGT</scene> as [http://en.wikipedia~~.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GK1 OCA].

2GK1 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GK1 OCA].

==Reference==

Crystallographic structure of human beta-hexosaminidase A: interpretation of Tay-Sachs mutations and loss of GM2 ganglioside hydrolysis., Lemieux MJ, Mark BL, Cherney MM, Withers SG, Mahuran DJ, James MN, J Mol Biol. 2006 Jun 16;359(4):913-29. Epub 2006 Apr 27. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~16698036 16698036]

Crystallographic structure of human beta-hexosaminidase A: interpretation of Tay-Sachs mutations and loss of GM2 ganglioside hydrolysis., Lemieux MJ, Mark BL, Cherney MM, Withers SG, Mahuran DJ, James MN, J Mol Biol. 2006 Jun 16;359(4):913-29. Epub 2006 Apr 27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16698036 16698036]

[[Category: Beta-N-acetylhexosaminidase]]

[[Category: Homo sapiens]]

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[[Category: Withers, S G.]]

[[Category: NGT]]

[[Category: beta-hexoasaminidase a]]

[[Category: beta-hexoasaminidase some]]

[[Category: glycosidase]]

[[Category: gm2 gangliodosis]]

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[[Category: tay-sachs disease]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu ~~Feb 21~~ 17:32:27 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:05:36 2008''

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@@ Line 1: / Line 1: @@
-[[Image:2gk1.gif|left|200px]]<br /><applet load="2gk1" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2gk1.gif|left|200px]]
-caption="2gk1, resolution 3.25&Aring;" />
-'''X-ray crystal structure of NGT-bound HexA'''<br />
+ {{Structure
+|PDB= 2gk1 |SIZE=350|CAPTION= <scene name='initialview01'>2gk1</scene>, resolution 3.25&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=NGT:3AR,5R,6S,7R,7AR-5-HYDROXYMETHYL-2-METHYL-5,6,7,7A-TETRAHYDRO-3AH-PYRANO[3,2-D]THIAZOLE-6,7-DIOL'>NGT</scene>
+|ACTIVITY= [http://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52]
+|GENE=
+}}
+'''X-ray crystal structure of NGT-bound HexA'''
 ==Overview==
@@ Line 10: / Line 19: @@
 ==About this Structure==
-GK1 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NGT:'>NGT</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Beta-N-acetylhexosaminidase Beta-N-acetylhexosaminidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.52 3.2.1.52] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GK1 OCA].
+GK1 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GK1 OCA].
 ==Reference==
-Crystallographic structure of human beta-hexosaminidase A: interpretation of Tay-Sachs mutations and loss of GM2 ganglioside hydrolysis., Lemieux MJ, Mark BL, Cherney MM, Withers SG, Mahuran DJ, James MN, J Mol Biol. 2006 Jun 16;359(4):913-29. Epub 2006 Apr 27. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16698036 16698036]
+Crystallographic structure of human beta-hexosaminidase A: interpretation of Tay-Sachs mutations and loss of GM2 ganglioside hydrolysis., Lemieux MJ, Mark BL, Cherney MM, Withers SG, Mahuran DJ, James MN, J Mol Biol. 2006 Jun 16;359(4):913-29. Epub 2006 Apr 27. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16698036 16698036]
 [[Category: Beta-N-acetylhexosaminidase]]
 [[Category: Homo sapiens]]
@@ Line 24: / Line 33: @@
 [[Category: Withers, S G.]]
 [[Category: NGT]]
-[[Category: beta-hexoasaminidase a]]
+[[Category: beta-hexoasaminidase some]]
 [[Category: glycosidase]]
 [[Category: gm2 gangliodosis]]
@@ Line 31: / Line 40: @@
 [[Category: tay-sachs disease]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:32:27 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:05:36 2008''