2m7f: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_2m7f|  PDB=2m7f  |  SCENE=  }}
===The C-terminal Region of Disintegrin Modulate its 3D Conformation and Cooperate with RGD Loop in Regulating Integrins Recognitions===


The entry 2m7f is ON HOLD
==Function==
[[http://www.uniprot.org/uniprot/VM2RH_CALRH VM2RH_CALRH]] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity).  Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3).


Authors: Chuang, W., Chang, Y.
==About this Structure==
 
[[2m7f]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Calloselasma_rhodostoma Calloselasma rhodostoma]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M7F OCA].  
Description: The C-terminal Region of Disintegrin Modulate its 3D Conformation and Cooperate with RGD Loop in Regulating Integrins Recognitions
[[Category: Calloselasma rhodostoma]]
[[Category: Chang, Y.]]
[[Category: Chuang, W.]]
[[Category: C-terminal region mutation]]
[[Category: Hydrolase]]
[[Category: Rgd motif]]
[[Category: Rhodostomin mutant protein]]