2m7f: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_2m7f| PDB=2m7f | SCENE= }} | |||
===The C-terminal Region of Disintegrin Modulate its 3D Conformation and Cooperate with RGD Loop in Regulating Integrins Recognitions=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/VM2RH_CALRH VM2RH_CALRH]] Metalloproteinase rhodostoxin: snake venom metalloproteinase that impairs hemostasis in the envenomed animal (By similarity). Disintegrin rhodostomin: inhibit platelet aggregation induced by ADP, thrombin, platelet-activating factor and collagen. Acts by inhibiting fibrinogen interaction with platelet receptors GPIIb/GPIIIa (ITGA2B/ITGB3). | |||
==About this Structure== | |||
[[2m7f]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Calloselasma_rhodostoma Calloselasma rhodostoma]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M7F OCA]. | |||
[[Category: Calloselasma rhodostoma]] | |||
[[Category: Chang, Y.]] | |||
[[Category: Chuang, W.]] | |||
[[Category: C-terminal region mutation]] | |||
[[Category: Hydrolase]] | |||
[[Category: Rgd motif]] | |||
[[Category: Rhodostomin mutant protein]] | |||