4bmb: Difference between revisions
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{{STRUCTURE_4bmb| PDB=4bmb | SCENE= }} | |||
===Crystal structure of the N terminal domain of human Galectin 8=== | |||
{{ABSTRACT_PUBMED_24418318}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/LEG8_HUMAN LEG8_HUMAN]] Lectin with a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.<ref>PMID:21288902</ref> | |||
==About this Structure== | |||
[[4bmb]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BMB OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024418318</ref><references group="xtra"/><references/> | |||
[[Category: Buzamet, E.]] | |||
[[Category: Gabius, H J.]] | |||
[[Category: Menendez, M.]] | |||
[[Category: Romero, A.]] | |||
[[Category: Ruiz, F M.]] | |||
[[Category: Solis, D.]] | |||
[[Category: Carbohydrate recognition]] | |||
[[Category: Sugar binding protein]] | |||
Revision as of 08:57, 19 March 2014
Crystal structure of the N terminal domain of human Galectin 8
Template:ABSTRACT PUBMED 24418318
Function
[LEG8_HUMAN] Lectin with a marked preference for 3'-O-sialylated and 3'-O-sulfated glycans.[1]
About this Structure
4bmb is a 1 chain structure. Full crystallographic information is available from OCA.
Reference
- Ruiz FM, Scholz BA, Buzamet E, Kopitz J, Andre S, Menendez M, Romero A, Solis D, Gabius HJ. Natural single amino acid polymorphism (F19Y) in human galectin-8: detection of structural alterations and increased growth-regulatory activity on tumor cells. FEBS J. 2014 Mar;281(5):1446-64. doi: 10.1111/febs.12716. Epub 2014 Feb 3. PMID:24418318 doi:https://dx.doi.org/10.1111/febs.12716
- ↑ Ideo H, Matsuzaka T, Nonaka T, Seko A, Yamashita K. Galectin-8-N-domain recognition mechanism for sialylated and sulfated glycans. J Biol Chem. 2011 Apr 1;286(13):11346-55. Epub 2011 Feb 2. PMID:21288902 doi:10.1074/jbc.M110.195925