4jv4: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4jv4|  PDB=4jv4  |  SCENE=  }}
===Crystal Structure of RIalpha(91-379) bound to HE33, a N6 di-propyl substituted cAMP analog===
{{ABSTRACT_PUBMED_23978166}}


The entry 4jv4 is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/KAP0_BOVIN KAP0_BOVIN]] Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.


Authors: Brown, S.H.J., Cheng, C.Y., Saldanha, A.S., Wu, J., Cottam, H., Sankaran, B., Taylor, S.S.
==About this Structure==
[[4jv4]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JV4 OCA].  


Description: Crystal Structure of RIalpha(91-379) bound to HE33, a N6 di-propyl substituted cAMP analog
==Reference==
<ref group="xtra">PMID:023978166</ref><references group="xtra"/><references/>
[[Category: Bos taurus]]
[[Category: Brown, S H.J.]]
[[Category: Cheng, C Y.]]
[[Category: Cottam, H.]]
[[Category: Saldanha, A S.]]
[[Category: Sankaran, B.]]
[[Category: Taylor, S S.]]
[[Category: Wu, J.]]
[[Category: Camp-dependent protein kinase]]
[[Category: Cyclic nucleotide analog]]
[[Category: Fluorescence anisotropy]]
[[Category: Isoform selectivity]]
[[Category: Transferase-transferase inhibitor complex]]

Revision as of 04:11, 20 September 2013

Template:STRUCTURE 4jv4

Crystal Structure of RIalpha(91-379) bound to HE33, a N6 di-propyl substituted cAMP analog

Template:ABSTRACT PUBMED 23978166

Function

[KAP0_BOVIN] Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.

About this Structure

4jv4 is a 1 chain structure with sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

  1. Brown SH, Cheng CY, Saldanha SA, Wu J, Cottam HB, Sankaran B, Taylor SS. Implementing Fluorescence Anisotropy Screening and Crystallographic Analysis to Define PKA Isoform-Selective Activation by cAMP Analogs. ACS Chem Biol. 2013 Sep 10. PMID:23978166 doi:10.1021/cb400247t

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