4k6m: Difference between revisions
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{{STRUCTURE_4k6m| PDB=4k6m | SCENE= }} | |||
===Crystal Structure of the full-length Japanese encephalitis virus NS5=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/Q5NT71_9FLAV Q5NT71_9FLAV]] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS000336_004_099774] | |||
==About this Structure== | |||
[[4k6m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Japanese_encephalitis_virus Japanese encephalitis virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K6M OCA]. | |||
[[Category: Japanese encephalitis virus]] | |||
[[Category: Gong, P.]] | |||
[[Category: Lu, G.]] | |||
[[Category: Methyltransferase]] | |||
[[Category: Rna-dependent rna polymerase]] | |||
[[Category: Transferase]] | |||
Revision as of 07:39, 28 August 2013
Crystal Structure of the full-length Japanese encephalitis virus NS5
Function
[Q5NT71_9FLAV] Envelope protein E binding to host cell surface receptor is followed by virus internalization through clathrin-mediated endocytosis. Envelope protein E is subsequently involved in membrane fusion between virion and host late endosomes. Synthesized as a homodimer with prM which acts as a chaperone for envelope protein E. After cleavage of prM, envelope protein E dissociate from small envelope protein M and homodimerizes (By similarity).[SAAS:SAAS000336_004_099774]
About this Structure
4k6m is a 2 chain structure with sequence from Japanese encephalitis virus. Full crystallographic information is available from OCA.
