3rok: Difference between revisions
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==See Also== | ==See Also== | ||
*[[Cluster of Differentiation | *[[Cluster of Differentiation CD38|Cluster of Differentiation CD38]] | ||
==Reference== | ==Reference== | ||
Revision as of 10:58, 3 July 2013
Crystal structure of human CD38 in complex with compound CZ-27
Template:ABSTRACT PUBMED 22142305
Function
[CD38_HUMAN] Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
About this Structure
3rok is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Kwong AK, Chen Z, Zhang H, Leung FP, Lam CM, Ting KY, Zhang L, Hao Q, Zhang LH, Lee HC. Catalysis-Based Inhibitors of the Calcium Signaling Function of CD38. Biochemistry. 2011 Dec 14. PMID:22142305 doi:10.1021/bi201509f
