1vtl: Difference between revisions

Line 1:

~~{{STRUCTURE_1vtl| PDB=1vtl | SCENE= }}~~

==CO-CRYSTAL STRUCTURE OF TBP RECOGNIZING THE MINOR GROOVE OF A TATA ELEMENT==

===CO-CRYSTAL STRUCTURE OF TBP RECOGNIZING THE MINOR GROOVE OF A TATA ELEMENT===

~~{{ABSTRACT_PUBMED_8413605}}~~

== Structural highlights ==

<table><tr><td colspan='2'>[[1vtl]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VTL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VTL FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vtl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vtl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1vtl RCSB], [http://www.ebi.ac.uk/pdbsum/1vtl PDBsum]</span></td></tr>

</table>

== Publication Abstract from PubMed ==

The three-dimensional structure of a TATA-box binding polypeptide complexed with the TATA element of the adenovirus major late promoter has been determined by X-ray crystallography at 2.25 A resolution. Binding of the saddle-shaped protein induces a conformational change in the DNA, inducing sharp kinks at either end of the sequence TATAAAAG. Between the kinks, the right-handed double helix is smoothly curved and partially unwound, presenting a widened minor groove to TBP's concave, antiparallel beta-sheet. Side-chain/base interactions are restricted to the minor groove, and include hydrogen bonds, van der Waals contacts and phenylalanine-base stacking interactions.

~~==About this Structure==~~

Co-crystal structure of TBP recognizing the minor groove of a TATA element.,Kim JL, Nikolov DB, Burley SK Nature. 1993 Oct 7;365(6446):520-7. PMID:8413605<ref>PMID:8413605</ref>

~~[[1vtl]] is~~ a ~~6 chain structure with sequence from [http://en~~.~~wikipedia~~.~~org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]~~. ~~Full crystallographic information is available from [http~~:/~~/oca.weizmann.ac.il/oca-bin/ocashort?id=1VTL OCA].~~

==~~Reference~~==

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>

~~<ref group="xtra">PMID:008413605</ref>~~<references ~~group="xtra"~~/><~~references~~/>

</div>

== References ==

__TOC__

</StructureSection>

[[Category: Arabidopsis thaliana]]

[[Category: Burley, S K.]]

[[Category: Burley, S K]]

[[Category: Kim, J L.]]

[[Category: Kim, J L]]

[[Category: Nikolov, D B.]]

[[Category: Nikolov, D B]]

[[Category: Double helix]]

[[Category: Protein-dna complex]]

[[Category: Transcription-dna complex]]

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@@ Line 1: / Line 1: @@
-{{STRUCTURE_1vtl|  PDB=1vtl  |  SCENE=  }}
+==CO-CRYSTAL STRUCTURE OF TBP RECOGNIZING THE MINOR GROOVE OF A TATA ELEMENT==
-===CO-CRYSTAL STRUCTURE OF TBP RECOGNIZING THE MINOR GROOVE OF A TATA ELEMENT===
+<StructureSection load='1vtl' size='340' side='right' caption='[[1vtl]], [[Resolution|resolution]] 2.25&Aring;' scene=''>
-{{ABSTRACT_PUBMED_8413605}}
+== Structural highlights ==
+<table><tr><td colspan='2'>[[1vtl]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VTL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1VTL FirstGlance]. <br>
+</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1vtl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vtl OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1vtl RCSB], [http://www.ebi.ac.uk/pdbsum/1vtl PDBsum]</span></td></tr>
+</table>
+<div style="background-color:#fffaf0;">
+== Publication Abstract from PubMed ==
+The three-dimensional structure of a TATA-box binding polypeptide complexed with the TATA element of the adenovirus major late promoter has been determined by X-ray crystallography at 2.25 A resolution. Binding of the saddle-shaped protein induces a conformational change in the DNA, inducing sharp kinks at either end of the sequence TATAAAAG. Between the kinks, the right-handed double helix is smoothly curved and partially unwound, presenting a widened minor groove to TBP's concave, antiparallel beta-sheet. Side-chain/base interactions are restricted to the minor groove, and include hydrogen bonds, van der Waals contacts and phenylalanine-base stacking interactions.
-==About this Structure==
+Co-crystal structure of TBP recognizing the minor groove of a TATA element.,Kim JL, Nikolov DB, Burley SK Nature. 1993 Oct 7;365(6446):520-7. PMID:8413605<ref>PMID:8413605</ref>
-[[1vtl]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Arabidopsis_thaliana Arabidopsis thaliana]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VTL OCA].
-==Reference==
+From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-<ref group="xtra">PMID:008413605</ref><references group="xtra"/><references/>
+</div>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
 [[Category: Arabidopsis thaliana]]
-[[Category: Burley, S K.]]
+[[Category: Burley, S K]]
-[[Category: Kim, J L.]]
+[[Category: Kim, J L]]
-[[Category: Nikolov, D B.]]
+[[Category: Nikolov, D B]]
 [[Category: Double helix]]
 [[Category: Protein-dna complex]]
 [[Category: Transcription-dna complex]]