3wrp: Difference between revisions
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Revision as of 08:09, 16 May 2013
FLEXIBILITY OF THE DNA-BINDING DOMAINS OF TRP REPRESSOR
Template:ABSTRACT PUBMED 3375234
Function
[TRPR_ECOLI] This protein is an aporepressor. When complexed with L-tryptophan it binds the operator region of the trp operon (5'-ACTAGT-'3') and prevents the initiation of transcription. The complex also regulates trp repressor biosynthesis by binding to its regulatory region.
About this Structure
3wrp is a 1 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
- Lawson CL, Zhang RG, Schevitz RW, Otwinowski Z, Joachimiak A, Sigler PB. Flexibility of the DNA-binding domains of trp repressor. Proteins. 1988;3(1):18-31. PMID:3375234 doi:https://dx.doi.org/10.1002/prot.340030103
