2gvz: Difference between revisions

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[[Image:2gvz.gif|left|200px]]<br /><applet load="2gvz" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2gvz.gif|left|200px]]
caption="2gvz, resolution 3.27&Aring;" />
 
'''Crystal Structure of Complex of Gs- with The Catalytic Domains of Mammalian Adenylyl Cyclase: Complex with MANT-ATP and Mn'''<br />
{{Structure
|PDB= 2gvz |SIZE=350|CAPTION= <scene name='initialview01'>2gvz</scene>, resolution 3.27&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GSP:5'-GUANOSINE-DIPHOSPHATE-MONOTHIOPHOSPHATE'>GSP</scene>, <scene name='pdbligand=FKP:METHYLPIPERAZINOFORSKOLIN'>FKP</scene> and <scene name='pdbligand=ONA:3'-O-[2-(METHYLAMINO)BENZOYL]ADENOSINE 5'-(TETRAHYDROGEN TRIPHOSPHATE)'>ONA</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Adenylate_cyclase Adenylate cyclase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.1 4.6.1.1]
|GENE= ADENYLYL CYCLASE TYPE V ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9615 Canis lupus familiaris]), ADENYLYL CYCLASE TYPE II ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus]), GNAS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 Bos taurus])
}}
 
'''Crystal Structure of Complex of Gs- with The Catalytic Domains of Mammalian Adenylyl Cyclase: Complex with MANT-ATP and Mn'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2GVZ is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [http://en.wikipedia.org/wiki/Canis_lupus_familiaris Canis lupus familiaris] and [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus] with <scene name='pdbligand=MN:'>MN</scene>, <scene name='pdbligand=CL:'>CL</scene>, <scene name='pdbligand=GSP:'>GSP</scene>, <scene name='pdbligand=FKP:'>FKP</scene> and <scene name='pdbligand=ONA:'>ONA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Adenylate_cyclase Adenylate cyclase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.1 4.6.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVZ OCA].  
2GVZ is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus], [http://en.wikipedia.org/wiki/Canis_lupus_familiaris Canis lupus familiaris] and [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GVZ OCA].  


==Reference==
==Reference==
Broad specificity of mammalian adenylyl cyclase for interaction with 2',3'-substituted purine- and pyrimidine nucleotide inhibitors., Mou TC, Gille A, Suryanarayana S, Richter M, Seifert R, Sprang SR, Mol Pharmacol. 2006 Sep;70(3):878-86. Epub 2006 Jun 9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16766715 16766715]
Broad specificity of mammalian adenylyl cyclase for interaction with 2',3'-substituted purine- and pyrimidine nucleotide inhibitors., Mou TC, Gille A, Suryanarayana S, Richter M, Seifert R, Sprang SR, Mol Pharmacol. 2006 Sep;70(3):878-86. Epub 2006 Jun 9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16766715 16766715]
[[Category: Adenylate cyclase]]
[[Category: Adenylate cyclase]]
[[Category: Bos taurus]]
[[Category: Bos taurus]]
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[[Category: mant-atp]]
[[Category: mant-atp]]


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Retrieved from "https://proteopedia.org/2gvz"