2m9f: Difference between revisions

Line 1:

~~'''Unreleased~~ structure~~'''~~

===NMR solution structure of Pin1 WW domain mutant 5-1g===

~~The entry 2m9f is ON HOLD~~

==Function==

[[http://www.uniprot.org/uniprot/PIN1_HUMAN PIN1_HUMAN]] Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation.<ref>PMID:15664191</ref> <ref>PMID:16644721</ref> <ref>PMID:21497122</ref>

~~Authors~~: ~~Enck, S., Chen, W., Price, J.L., Powers, E.T., Wong, C., Dyson, H~~.J.~~, Kelly, J~~.W.

==About this Structure==

[[2m9f]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M9F OCA].

~~Description~~: ~~NMR solution structure of Pin1 WW~~ domain ~~mutant 5-1g~~

==Reference==

[[Category: Chen, W.]]

[[Category: Dyson, H J.]]

[[Category: Enck, S.]]

[[Category: Kelly, J W.]]

[[Category: Powers, E T.]]

[[Category: Price, J L.]]

[[Category: Wong, C.]]

[[Category: Ch-pi interaction]]

[[Category: Enhanced aromatic sequon]]

[[Category: Isomerase]]

[[Category: N-glycosylation]]

[[Category: Ww domain]]

Navigation menu

Page actions

Page actions

Personal tools

Navigation

Search

Tools

@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+{{STRUCTURE_2m9f|  PDB=2m9f  |  SCENE=  }}
+===NMR solution structure of Pin1 WW domain mutant 5-1g===
-The entry 2m9f is ON HOLD
+==Function==
+[[http://www.uniprot.org/uniprot/PIN1_HUMAN PIN1_HUMAN]] Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an acidic residue N-terminal to the isomerized proline bond. Catalyzes pSer/Thr-Pro cis/trans isomerizations. Down-regulates kinase activity of BTK. Can transactivate multiple oncogenes and induce centrosome amplification, chromosome instability and cell transformation. Required for the efficient dephosphorylation and recycling of RAF1 after mitogen activation.<ref>PMID:15664191</ref> <ref>PMID:16644721</ref> <ref>PMID:21497122</ref>
-Authors: Enck, S., Chen, W., Price, J.L., Powers, E.T., Wong, C., Dyson, H.J., Kelly, J.W.
+==About this Structure==
+[[2m9f]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2M9F OCA].
-Description: NMR solution structure of Pin1 WW domain mutant 5-1g
+==Reference==
+<references group="xtra"/><references/>
+[[Category: Chen, W.]]
+[[Category: Dyson, H J.]]
+[[Category: Enck, S.]]
+[[Category: Kelly, J W.]]
+[[Category: Powers, E T.]]
+[[Category: Price, J L.]]
+[[Category: Wong, C.]]
+[[Category: Ch-pi interaction]]
+[[Category: Enhanced aromatic sequon]]
+[[Category: Isomerase]]
+[[Category: N-glycosylation]]
+[[Category: Ww domain]]