3wbq: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_3wbq|  PDB=3wbq  |  SCENE=  }}
===Crystal structure of carbohydrate recognition domain of Blood Dendritic Cell Antigen-2 (BDCA2) lectin (crystal form-2)===


The entry 3wbq is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/CLC4C_HUMAN CLC4C_HUMAN]] Involved in antigen-capturing. Target ligand into antigen processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium. Does not seem to bind mannose.<ref>PMID:11748283</ref> <ref>PMID:11031109</ref>  


Authors: Nagae, M., Yamaguchi, Y.
==About this Structure==
[[3wbq]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WBQ OCA].  


Description: Crystal structure of lectin (crystal form-2)
==Reference==
<references group="xtra"/><references/>
[[Category: Ikeda, A.]]
[[Category: Kitago, Y.]]
[[Category: Matsumoto, N.]]
[[Category: Nagae, M.]]
[[Category: Yamaguchi, Y.]]
[[Category: Yamamoto, K.]]
[[Category: C-type lectin fold]]
[[Category: Carbohydrate binding protein]]
[[Category: Complex-type n-glycan]]
[[Category: Immune receptor]]