3wbq: Difference between revisions
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{{STRUCTURE_3wbq| PDB=3wbq | SCENE= }} | |||
===Crystal structure of carbohydrate recognition domain of Blood Dendritic Cell Antigen-2 (BDCA2) lectin (crystal form-2)=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CLC4C_HUMAN CLC4C_HUMAN]] Involved in antigen-capturing. Target ligand into antigen processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium. Does not seem to bind mannose.<ref>PMID:11748283</ref> <ref>PMID:11031109</ref> | |||
==About this Structure== | |||
[[3wbq]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WBQ OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: Ikeda, A.]] | |||
[[Category: Kitago, Y.]] | |||
[[Category: Matsumoto, N.]] | |||
[[Category: Nagae, M.]] | |||
[[Category: Yamaguchi, Y.]] | |||
[[Category: Yamamoto, K.]] | |||
[[Category: C-type lectin fold]] | |||
[[Category: Carbohydrate binding protein]] | |||
[[Category: Complex-type n-glycan]] | |||
[[Category: Immune receptor]] | |||