4bn5: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4bn5|  PDB=4bn5  |  SCENE=  }}
===Structure of human SIRT3 in complex with SRT1720 inhibitor===


The entry 4bn5 is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/SIR3_HUMAN SIR3_HUMAN]] NAD-dependent protein deacetylase. Activates mitochondrial target proteins, including ACSS1, IDH2 and GDH by deacetylating key lysine residues. Contributes to the regulation of the cellular energy metabolism. Important for regulating tissue-specific ATP levels.<ref>PMID:16788062</ref> <ref>PMID:18680753</ref> <ref>PMID:18794531</ref> <ref>PMID:19535340</ref>  


Authors: Nguyen, G.T.T., Schaefer, S., Gert, M., Weyand, M., Steegborn, C.
==About this Structure==
[[4bn5]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BN5 OCA].  


Description: Structure of human SIRT3 in complex with SRT1720 inhibitor
==Reference==
<references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Gertz, M.]]
[[Category: Nguyen, G T.T.]]
[[Category: Schaefer, S.]]
[[Category: Steegborn, C.]]
[[Category: Weyand, M.]]
[[Category: Adp ribose]]
[[Category: Hydrolase]]
[[Category: Lysine deacetylase]]