2gyw: Difference between revisions

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[[Image:2gyw.gif|left|200px]]<br /><applet load="2gyw" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2gyw.gif|left|200px]]
caption="2gyw, resolution 2.400&Aring;" />
 
'''Crystal Structure of Mus musculus Acetylcholinesterase in Complex with Obidoxime'''<br />
{{Structure
|PDB= 2gyw |SIZE=350|CAPTION= <scene name='initialview01'>2gyw</scene>, resolution 2.400&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=OBI:1,1'-(OXYDIMETHYLENE)BIS(4-FORMYLPYRIDINIUM)DIOXIME'>OBI</scene> and <scene name='pdbligand=P6G:HEXAETHYLENE GLYCOL'>P6G</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7]
|GENE= Ache ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
}}
 
'''Crystal Structure of Mus musculus Acetylcholinesterase in Complex with Obidoxime'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2GYW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=NAG:'>NAG</scene>, <scene name='pdbligand=CO3:'>CO3</scene>, <scene name='pdbligand=OBI:'>OBI</scene> and <scene name='pdbligand=P6G:'>P6G</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GYW OCA].  
2GYW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GYW OCA].  


==Reference==
==Reference==
Crystal structures of acetylcholinesterase in complex with HI-6, Ortho-7 and obidoxime: structural basis for differences in the ability to reactivate tabun conjugates., Ekstrom F, Pang YP, Boman M, Artursson E, Akfur C, Borjegren S, Biochem Pharmacol. 2006 Aug 28;72(5):597-607. Epub 2006 Jul 31. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16876764 16876764]
Crystal structures of acetylcholinesterase in complex with HI-6, Ortho-7 and obidoxime: structural basis for differences in the ability to reactivate tabun conjugates., Ekstrom F, Pang YP, Boman M, Artursson E, Akfur C, Borjegren S, Biochem Pharmacol. 2006 Aug 28;72(5):597-607. Epub 2006 Jul 31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16876764 16876764]
[[Category: Acetylcholinesterase]]
[[Category: Acetylcholinesterase]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: reactivator]]
[[Category: reactivator]]


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