2gz7: Difference between revisions

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[[Image:2gz7.gif|left|200px]]<br /><applet load="2gz7" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2gz7.gif|left|200px]]
caption="2gz7, resolution 1.856&Aring;" />
 
'''Structure-Based Drug Design and Structural Biology Study of Novel Nonpeptide Inhibitors of SARS-CoV Main Protease'''<br />
{{Structure
|PDB= 2gz7 |SIZE=350|CAPTION= <scene name='initialview01'>2gz7</scene>, resolution 1.856&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=D3F:2-[(2,4-DICHLORO-5-METHYLPHENYL)SULFONYL]-1,3-DINITRO-5-(TRIFLUOROMETHYL)BENZENE'>D3F</scene>
|ACTIVITY=
|GENE=
}}
 
'''Structure-Based Drug Design and Structural Biology Study of Novel Nonpeptide Inhibitors of SARS-CoV Main Protease'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2GZ7 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Sars_coronavirus Sars coronavirus] with <scene name='pdbligand=D3F:'>D3F</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GZ7 OCA].  
2GZ7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Sars_coronavirus Sars coronavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GZ7 OCA].  


==Reference==
==Reference==
Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease., Lu IL, Mahindroo N, Liang PH, Peng YH, Kuo CJ, Tsai KC, Hsieh HP, Chao YS, Wu SY, J Med Chem. 2006 Aug 24;49(17):5154-61. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16913704 16913704]
Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease., Lu IL, Mahindroo N, Liang PH, Peng YH, Kuo CJ, Tsai KC, Hsieh HP, Chao YS, Wu SY, J Med Chem. 2006 Aug 24;49(17):5154-61. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16913704 16913704]
[[Category: Sars coronavirus]]
[[Category: Sars coronavirus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: sars cov main protease]]
[[Category: sars cov main protease]]


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