4bpw: Difference between revisions
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{{STRUCTURE_4bpw| PDB=4bpw | SCENE= }} | |||
===Crystal structure of human primase bound to UTP=== | |||
{{ABSTRACT_PUBMED_24043831}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/PRI1_HUMAN PRI1_HUMAN]] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. [[http://www.uniprot.org/uniprot/PRI2_HUMAN PRI2_HUMAN]] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. | |||
==About this Structure== | |||
[[4bpw]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BPW OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024043831</ref><references group="xtra"/><references/> | |||
[[Category: Homo sapiens]] | |||
[[Category: Kilkenny, M L.]] | |||
[[Category: Pellegrini, L.]] | |||
[[Category: Perera, R L.]] | |||
[[Category: Dna replication]] | |||
[[Category: Dna-dependent rna polymerase]] | |||
[[Category: Transferase]] | |||
Revision as of 08:11, 29 September 2013
Crystal structure of human primase bound to UTP
Template:ABSTRACT PUBMED 24043831
Function
[PRI1_HUMAN] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication. [PRI2_HUMAN] DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.
About this Structure
4bpw is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Kilkenny ML, Longo MA, Perera RL, Pellegrini L. Structures of human primase reveal design of nucleotide elongation site and mode of Pol alpha tethering. Proc Natl Acad Sci U S A. 2013 Sep 16. PMID:24043831 doi:10.1073/pnas.1311185110