4juo: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4juo|  PDB=4juo  |  SCENE=  }}
===A low-resolution three-gate structure of topoisomerase IV from Streptococcus pneumoniae in space group H32===


The entry 4juo is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/PARC_STRPN PARC_STRPN]] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.<ref>PMID:17375187</ref> <ref>PMID:20596531</ref>  [[http://www.uniprot.org/uniprot/PARE_STRPN PARE_STRPN]] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.<ref>PMID:17375187</ref> <ref>PMID:20596531</ref>  


Authors: Laponogov, I., Veselkov, D.A., Pan, X.-S., Crevel, I., Fisher, L.M., Sanderson, M.R.
==About this Structure==
[[4juo]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Gekko_coi Gekko coi] and [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae_tigr4 Streptococcus pneumoniae tigr4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JUO OCA].  


Description: A low-resolution three-gate structure of topoisomerase IV from Streptococcus pneumoniae in space group H32
==Reference==
<references group="xtra"/><references/>
[[Category: Gekko coi]]
[[Category: Streptococcus pneumoniae tigr4]]
[[Category: Crevel, I.]]
[[Category: Fisher, L M.]]
[[Category: Laponogov, I.]]
[[Category: Pan, X S.]]
[[Category: Sanderson, M R.]]
[[Category: Veselkov, D A.]]
[[Category: Atp binding]]
[[Category: Full-length pare]]
[[Category: Isomerase-dna complex]]
[[Category: Open n-gate]]
[[Category: Parc55]]
[[Category: Topoisomerase iia]]

Revision as of 07:38, 28 August 2013

Template:STRUCTURE 4juo

A low-resolution three-gate structure of topoisomerase IV from Streptococcus pneumoniae in space group H32

Function

[PARC_STRPN] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.[1] [2] [PARE_STRPN] Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.[3] [4]

About this Structure

4juo is a 6 chain structure with sequence from Gekko coi and Streptococcus pneumoniae tigr4. Full crystallographic information is available from OCA.

Reference

  1. ↑ Laponogov I, Veselkov DA, Sohi MK, Pan XS, Achari A, Yang C, Ferrara JD, Fisher LM, Sanderson MR. Breakage-reunion domain of Streptococcus pneumoniae topoisomerase IV: crystal structure of a gram-positive quinolone target. PLoS ONE. 2007 Mar 21;2(3):e301. PMID:17375187 doi:10.1371/journal.pone.0000301
  2. ↑ Laponogov I, Pan XS, Veselkov DA, McAuley KE, Fisher LM, Sanderson MR. Structural basis of gate-DNA breakage and resealing by type II topoisomerases. PLoS One. 2010 Jun 28;5(6):e11338. PMID:20596531 doi:10.1371/journal.pone.0011338
  3. ↑ Laponogov I, Veselkov DA, Sohi MK, Pan XS, Achari A, Yang C, Ferrara JD, Fisher LM, Sanderson MR. Breakage-reunion domain of Streptococcus pneumoniae topoisomerase IV: crystal structure of a gram-positive quinolone target. PLoS ONE. 2007 Mar 21;2(3):e301. PMID:17375187 doi:10.1371/journal.pone.0000301
  4. ↑ Laponogov I, Pan XS, Veselkov DA, McAuley KE, Fisher LM, Sanderson MR. Structural basis of gate-DNA breakage and resealing by type II topoisomerases. PLoS One. 2010 Jun 28;5(6):e11338. PMID:20596531 doi:10.1371/journal.pone.0011338

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