4kbm: Difference between revisions
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{{STRUCTURE_4kbm| PDB=4kbm | SCENE= }} | |||
===Structure of the Mtb CarD/RNAP Beta subunit B1-B2 domains complex=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/RPOB_MYCTU RPOB_MYCTU]] DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.[HAMAP-Rule:MF_01321] [[http://www.uniprot.org/uniprot/CARD_MYCTU CARD_MYCTU]] Controls rRNA transcription by binding to the RNA polymerase (RNAP). Required for replication and persistence during infection of mice.<ref>PMID:19596241</ref> <ref>PMID:22904282</ref> | |||
==About this Structure== | |||
[[4kbm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KBM OCA]. | |||
==Reference== | |||
<references group="xtra"/><references/> | |||
[[Category: DNA-directed RNA polymerase]] | |||
[[Category: Mycobacterium tuberculosis]] | |||
[[Category: Gulten, G.]] | |||
[[Category: Sacchettini, J C.]] | |||
[[Category: TBSGC, TB Structural Genomics Consortium.]] | |||
[[Category: Card]] | |||
[[Category: Dna]] | |||
[[Category: Dna-dependent rna polymerase]] | |||
[[Category: Protein-protein complex]] | |||
[[Category: Sigma factor]] | |||
[[Category: Structural genomic]] | |||
[[Category: Tb structural genomics consortium]] | |||
[[Category: Tbsgc]] | |||
[[Category: Transcription regulator]] | |||
[[Category: Transferase-transcription complex]] | |||
[[Category: Tudor]] | |||