4kgb: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_4kgb| PDB=4kgb | SCENE= }} | |||
===Structure of succinyl-CoA: 3-ketoacid CoA transferase from Drosophila melanogaster=== | |||
{{ABSTRACT_PUBMED_24100554}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/Q9W058_DROME Q9W058_DROME]] Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate (By similarity).[PIRNR:PIRNR000858] | |||
==About this Structure== | |||
[[4kgb]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KGB OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:024100554</ref><references group="xtra"/><references/> | |||
[[Category: 3-oxoacid CoA-transferase]] | |||
[[Category: Drosophila melanogaster]] | |||
[[Category: Shi, Z B.]] | |||
[[Category: Wang, Y C.]] | |||
[[Category: Zhang, M.]] | |||
[[Category: Ketone body catabolic process]] | |||
[[Category: Protein fold]] | |||
[[Category: Transferase]] | |||
Revision as of 06:44, 23 October 2013
Structure of succinyl-CoA: 3-ketoacid CoA transferase from Drosophila melanogaster
Template:ABSTRACT PUBMED 24100554
Function
[Q9W058_DROME] Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate (By similarity).[PIRNR:PIRNR000858]
About this Structure
4kgb is a 2 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA.
Reference
- Zhang M, Xu HY, Wang YC, Shi ZB, Zhang NN. Structure of succinyl-CoA:3-ketoacid CoA transferase from Drosophila melanogaster. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Oct;69(Pt 10):1089-93., doi: 10.1107/S1744309113024986. Epub 2013 Sep 28. PMID:24100554 doi:https://dx.doi.org/10.1107/S1744309113024986
