4kjl: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
{{STRUCTURE_4kjl| PDB=4kjl | SCENE= }} | |||
===Room Temperature N23PPS148A DHFR=== | |||
{{ABSTRACT_PUBMED_23913260}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/DYR_ECOLI DYR_ECOLI]] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | |||
==About this Structure== | |||
[[4kjl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KJL OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023913260</ref><references group="xtra"/><references/> | |||
[[Category: Dihydrofolate reductase]] | |||
[[Category: Escherichia coli k-12]] | |||
[[Category: Bedem, H van den.]] | |||
[[Category: Bhabha, G.]] | |||
[[Category: Fraser, J S.]] | |||
[[Category: Wright, P E.]] | |||
[[Category: Yang, K.]] | |||
[[Category: Oxidoreductase]] | |||
[[Category: Rossman fold]] | |||
Revision as of 08:25, 21 August 2013
Room Temperature N23PPS148A DHFR
Template:ABSTRACT PUBMED 23913260
Function
[DYR_ECOLI] Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
About this Structure
4kjl is a 1 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.
Reference
- van den Bedem H, Bhabha G, Yang K, Wright PE, Fraser JS. Automated identification of functional dynamic contact networks from X-ray crystallography. Nat Methods. 2013 Aug 4. doi: 10.1038/nmeth.2592. PMID:23913260 doi:10.1038/nmeth.2592
