4klb: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4klb|  PDB=4klb  |  SCENE=  }}
===Crystal Structure of Cruzain in complex with the non-covalent inhibitor Nequimed176===
{{ABSTRACT_PUBMED_23991231}}


The entry 4klb is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/CYSP_TRYCR CYSP_TRYCR]] Hydrolyzes chromogenic peptides at the carboxyl Arg or Lys; requires at least one more amino acid, preferably Arg, Phe, Val or Leu, between the terminal Arg or Lys and the amino-blocking group.  The cysteine protease may play an important role in the development and differentiation of the parasites at several stages of their life cycle.


Authors: Fernandes, W.B., Montanari, C.A., Mckerrow, J.H.
==About this Structure==
[[4klb]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_cruzi Trypanosoma cruzi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KLB OCA].  


Description: Crystal Structure of Cruzain in complex with the non-covalent inhibitor Nequimed176
==Reference==
<ref group="xtra">PMID:023991231</ref><references group="xtra"/><references/>
[[Category: Cruzipain]]
[[Category: Trypanosoma cruzi]]
[[Category: Fernandes, W B.]]
[[Category: Mckerrow, J H.]]
[[Category: Montanari, C A.]]
[[Category: Hydrolase]]
[[Category: Hydrolase-hydrolase inhibitor complex]]
[[Category: Protease]]
[[Category: Thiol protease]]
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