4klu: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4klu|  PDB=4klu  |  SCENE=  }}
===DNA polymerase beta mismatched product complex with Mn2+, 15 h===
{{ABSTRACT_PUBMED_23827680}}


The entry 4klu is ON HOLD until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/DPOLB_HUMAN DPOLB_HUMAN]] Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.<ref>PMID:9207062</ref> <ref>PMID:9572863</ref> <ref>PMID:11805079</ref> <ref>PMID:21362556</ref>  


Authors: Freudenthal, B.D., Beard, W.A., Shock, D.D., Wilson, S.H.
==About this Structure==
[[4klu]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KLU OCA].  


Description: DNA polymerase beta mismatched product complex with Mn2+, 15 h
==Reference==
<ref group="xtra">PMID:023827680</ref><references group="xtra"/><references/>
[[Category: Homo sapiens]]
[[Category: Beard, W A.]]
[[Category: Freudenthal, B D.]]
[[Category: Shock, D D.]]
[[Category: Wilson, S H.]]
[[Category: Dna polymerase]]
[[Category: Lyase-dna complex]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/4klu"