4kvi: Difference between revisions

Line 1:

~~'''Unreleased~~ structure~~'''~~

===Crystal structure of Aspergillus terreus aristolochene synthase complexed with (4aS,7S)-4a-methyl-7-(prop-1-en-2-yl)-2,3,4,4a,5,6,7,8-octahydroquinolin-1-ium===

~~The entry 4kvi~~ is ~~ON HOLD~~ ~~until Paper Publication~~

==Function==

[[http://www.uniprot.org/uniprot/ARIS_ASPTE ARIS_ASPTE]] Catalyzes the cyclization of trans,trans-farnesyl diphosphate (FPP) to the bicyclic sesquiterpene aristolochene. Produces germacrene A as an enzyme-bound intermediate that is not released by the enzyme, but is further cyclized to produce aristolochene. Aristolochene is the likely parent compound for a number of sesquiterpenoid toxins produced by filamentous fungi.<ref>PMID:10775423</ref> <ref>PMID:15186158</ref>

~~Authors~~: ~~Chen, M~~.~~, Faraldos, J~~.A.~~, Al-lami, N~~.~~, Janvier, M~~.~~, D'Antonio, E~~.~~L., Cane, D.E., Allemann, R.K., Christianson, D.W~~.

==About this Structure==

[[4kvi]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Aspergillus_terreus Aspergillus terreus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KVI OCA].

~~Description~~: ~~Crystal structure of~~ Aspergillus terreus ~~aristolochene synthase complexed with (4aS~~,~~7S)-4a-methyl-7-(prop-1-en-2-yl)-2~~,3,4,4a,5,6,7,8-~~octahydroquinolin~~-1-~~ium~~

==Reference==

[[Category: Aristolochene synthase]]

[[Category: Aspergillus terreus]]

[[Category: Al-lami, N.]]

[[Category: Allemann, R K.]]

[[Category: Antonio, E L.D.]]

[[Category: Cane, D E.]]

[[Category: Chen, M.]]

[[Category: Christianson, D W.]]

[[Category: Faraldos, J A.]]

[[Category: Janvier, M.]]

[[Category: Alpha-helical fold]]

[[Category: Class i terpene cyclase]]

[[Category: Farnesyl diphosphate]]

[[Category: Lyase-lyase inhibitor complex]]

[[Category: Magnesium]]

[[Category: Metal-binding]]

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-'''Unreleased structure'''
+{{STRUCTURE_4kvi|  PDB=4kvi  |  SCENE=  }}
+===Crystal structure of Aspergillus terreus aristolochene synthase complexed with (4aS,7S)-4a-methyl-7-(prop-1-en-2-yl)-2,3,4,4a,5,6,7,8-octahydroquinolin-1-ium===
+{{ABSTRACT_PUBMED_23905850}}
-The entry 4kvi is ON HOLD  until Paper Publication
+==Function==
+[[http://www.uniprot.org/uniprot/ARIS_ASPTE ARIS_ASPTE]] Catalyzes the cyclization of trans,trans-farnesyl diphosphate (FPP) to the bicyclic sesquiterpene aristolochene. Produces germacrene A as an enzyme-bound intermediate that is not released by the enzyme, but is further cyclized to produce aristolochene. Aristolochene is the likely parent compound for a number of sesquiterpenoid toxins produced by filamentous fungi.<ref>PMID:10775423</ref> <ref>PMID:15186158</ref>
-Authors: Chen, M., Faraldos, J.A., Al-lami, N., Janvier, M., D'Antonio, E.L., Cane, D.E., Allemann, R.K., Christianson, D.W.
+==About this Structure==
+[[4kvi]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Aspergillus_terreus Aspergillus terreus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4KVI OCA].
-Description: Crystal structure of Aspergillus terreus aristolochene synthase complexed with (4aS,7S)-4a-methyl-7-(prop-1-en-2-yl)-2,3,4,4a,5,6,7,8-octahydroquinolin-1-ium
+==Reference==
+<ref group="xtra">PMID:023905850</ref><references group="xtra"/><references/>
+[[Category: Aristolochene synthase]]
+[[Category: Aspergillus terreus]]
+[[Category: Al-lami, N.]]
+[[Category: Allemann, R K.]]
+[[Category: Antonio, E L.D.]]
+[[Category: Cane, D E.]]
+[[Category: Chen, M.]]
+[[Category: Christianson, D W.]]
+[[Category: Faraldos, J A.]]
+[[Category: Janvier, M.]]
+[[Category: Alpha-helical fold]]
+[[Category: Class i terpene cyclase]]
+[[Category: Farnesyl diphosphate]]
+[[Category: Lyase-lyase inhibitor complex]]
+[[Category: Magnesium]]
+[[Category: Metal-binding]]