2h9v: Difference between revisions

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[[Image:2h9v.gif|left|200px]]<br /><applet load="2h9v" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2h9v.gif|left|200px]]
caption="2h9v, resolution 3.100&Aring;" />
 
'''Structural basis for induced-fit binding of Rho-kinase to the inhibitor Y27632'''<br />
{{Structure
|PDB= 2h9v |SIZE=350|CAPTION= <scene name='initialview01'>2h9v</scene>, resolution 3.100&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=Y27:(R)-TRANS-4-(1-AMINOETHYL)-N-(4-PYRIDYL) CYCLOHEXANECARBOXAMIDE'>Y27</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1]
|GENE=
}}
 
'''Structural basis for induced-fit binding of Rho-kinase to the inhibitor Y27632'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2H9V is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus] with <scene name='pdbligand=Y27:'>Y27</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H9V OCA].  
2H9V is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H9V OCA].  


==Reference==
==Reference==
Structural basis for induced-fit binding of Rho-kinase to the inhibitor Y-27632., Yamaguchi H, Miwa Y, Kasa M, Kitano K, Amano M, Kaibuchi K, Hakoshima T, J Biochem. 2006 Sep;140(3):305-11. Epub 2006 Aug 4. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16891330 16891330]
Structural basis for induced-fit binding of Rho-kinase to the inhibitor Y-27632., Yamaguchi H, Miwa Y, Kasa M, Kitano K, Amano M, Kaibuchi K, Hakoshima T, J Biochem. 2006 Sep;140(3):305-11. Epub 2006 Aug 4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16891330 16891330]
[[Category: Bos taurus]]
[[Category: Bos taurus]]
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Non-specific serine/threonine protein kinase]]
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[[Category: protein kinase-inhibitor complex]]
[[Category: protein kinase-inhibitor complex]]


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