4b3a: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Tetracycline repressor class D mutant H100A in complex with tetracycline== | |||
<StructureSection load='4b3a' size='340' side='right' caption='[[4b3a]], [[Resolution|resolution]] 1.70Å' scene=''> | |||
== Structural highlights == | |||
==Function== | <table><tr><td colspan='2'>[[4b3a]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B3A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B3A FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TAC:TETRACYCLINE'>TAC</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b3a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b3a OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4b3a RCSB], [http://www.ebi.ac.uk/pdbsum/4b3a PDBsum]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/TETR4_ECOLX TETR4_ECOLX]] TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. | [[http://www.uniprot.org/uniprot/TETR4_ECOLX TETR4_ECOLX]] TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. | ||
== | ==See Also== | ||
[[ | *[[Tetracycline repressor protein|Tetracycline repressor protein]] | ||
__TOC__ | |||
</StructureSection> | |||
[[Category: Escherichia coli]] | [[Category: Escherichia coli]] | ||
[[Category: Eltschkner, S | [[Category: Eltschkner, S]] | ||
[[Category: Hinrichs, W | [[Category: Hinrichs, W]] | ||
[[Category: Palm, G J | [[Category: Palm, G J]] | ||
[[Category: Schindler, S | [[Category: Schindler, S]] | ||
[[Category: Schneider, J | [[Category: Schneider, J]] | ||
[[Category: Tet-repressor]] | [[Category: Tet-repressor]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
