2hmi: Difference between revisions

From Proteopedia
Jump to navigationJump to search
OCA (talk | contribs)
No edit summary
OCA (talk | contribs)
No edit summary
Line 1: Line 1:
[[Image:2hmi.gif|left|200px]]<br /><applet load="2hmi" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2hmi.gif|left|200px]]
caption="2hmi, resolution 2.80&Aring;" />
 
'''HIV-1 REVERSE TRANSCRIPTASE/FRAGMENT OF FAB 28/DNA COMPLEX'''<br />
{{Structure
|PDB= 2hmi |SIZE=350|CAPTION= <scene name='initialview01'>2hmi</scene>, resolution 2.80&Aring;
|SITE=
|LIGAND=
|ACTIVITY= [http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49]
|GENE=
}}
 
'''HIV-1 REVERSE TRANSCRIPTASE/FRAGMENT OF FAB 28/DNA COMPLEX'''
 


==Overview==
==Overview==
Line 7: Line 16:


==About this Structure==
==About this Structure==
2HMI is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry 1HMI. The following page contains interesting information on the relation of 2HMI with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb33_1.html Reverse Transcriptase]]. Active as [http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HMI OCA].  
2HMI is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry 1HMI. The following page contains interesting information on the relation of 2HMI with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb33_1.html Reverse Transcriptase]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HMI OCA].  


==Reference==
==Reference==
Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution., Ding J, Das K, Hsiou Y, Sarafianos SG, Clark AD Jr, Jacobo-Molina A, Tantillo C, Hughes SH, Arnold E, J Mol Biol. 1998 Dec 11;284(4):1095-111. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9837729 9837729]
Structure and functional implications of the polymerase active site region in a complex of HIV-1 RT with a double-stranded DNA template-primer and an antibody Fab fragment at 2.8 A resolution., Ding J, Das K, Hsiou Y, Sarafianos SG, Clark AD Jr, Jacobo-Molina A, Tantillo C, Hughes SH, Arnold E, J Mol Biol. 1998 Dec 11;284(4):1095-111. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9837729 9837729]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
Line 18: Line 27:
[[Category: Arnold, E.]]
[[Category: Arnold, E.]]
[[Category: Ding, J.]]
[[Category: Ding, J.]]
[[Category: aids]]
[[Category: aid]]
[[Category: hiv-1]]
[[Category: hiv-1]]
[[Category: polymerase]]
[[Category: polymerase]]
[[Category: rt]]
[[Category: rt]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:43:22 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:18:56 2008''