2lui: Difference between revisions
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==Structure of the PICK PDZ domain in complex with the DAT C-terminal== | |||
<StructureSection load='2lui' size='340' side='right' caption='[[2lui]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''> | |||
== Structural highlights == | |||
==Function== | <table><tr><td colspan='2'>[[2lui]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LUI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LUI FirstGlance]. <br> | ||
</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Pick1, Prkcabp ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10116 Rattus norvegicus])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lui FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lui OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2lui RCSB], [http://www.ebi.ac.uk/pdbsum/2lui PDBsum]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/PICK1_RAT PICK1_RAT]] Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel.<ref>PMID:16138078</ref> | [[http://www.uniprot.org/uniprot/PICK1_RAT PICK1_RAT]] Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel.<ref>PMID:16138078</ref> | ||
== References == | |||
== | <references/> | ||
__TOC__ | |||
</StructureSection> | |||
<references | |||
[[Category: Rattus norvegicus]] | [[Category: Rattus norvegicus]] | ||
[[Category: Erlendsson, S | [[Category: Erlendsson, S]] | ||
[[Category: Gether, U | [[Category: Gether, U]] | ||
[[Category: Heidarsson, P O | [[Category: Heidarsson, P O]] | ||
[[Category: Madsen, K L | [[Category: Madsen, K L]] | ||
[[Category: Poulsen, F M | [[Category: Poulsen, F M]] | ||
[[Category: Rathje, M | [[Category: Rathje, M]] | ||
[[Category: Teilum, K | [[Category: Teilum, K]] | ||
[[Category: Dat c-terminal]] | [[Category: Dat c-terminal]] | ||
[[Category: Pdz]] | [[Category: Pdz]] | ||
[[Category: Pick1]] | [[Category: Pick1]] | ||
[[Category: Protein binding]] | [[Category: Protein binding]] | ||
