4hzm: Difference between revisions
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{{STRUCTURE_4hzm| PDB=4hzm | SCENE= }} | {{STRUCTURE_4hzm| PDB=4hzm | SCENE= }} | ||
===Crystal structure of Salmonella typhimurium family 3 glycoside hydrolase (NagZ) bound to N-[(3S,4R,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)piperidin-3-yl]butanamide=== | ===Crystal structure of Salmonella typhimurium family 3 glycoside hydrolase (NagZ) bound to N-[(3S,4R,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)piperidin-3-yl]butanamide=== | ||
{{ABSTRACT_PUBMED_24009110}} | |||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
[[4hzm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/ | [[4hzm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salty Salty]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HZM OCA]. | ||
==See Also== | |||
*[[Beta-Hexosaminidase|Beta-Hexosaminidase]] | |||
==Reference== | |||
<ref group="xtra">PMID:024009110</ref><references group="xtra"/><references/> | |||
[[Category: Beta-N-acetylhexosaminidase]] | [[Category: Beta-N-acetylhexosaminidase]] | ||
[[Category: | [[Category: Salty]] | ||
[[Category: Bacik, J P.]] | [[Category: Bacik, J P.]] | ||
[[Category: Mark, B L.]] | [[Category: Mark, B L.]] | ||
[[Category: Hydrolase-hydrolase inhibitor complex]] | [[Category: Hydrolase-hydrolase inhibitor complex]] | ||
[[Category: Tim-barrel]] | [[Category: Tim-barrel]] | ||
Revision as of 06:55, 13 November 2013
Crystal structure of Salmonella typhimurium family 3 glycoside hydrolase (NagZ) bound to N-[(3S,4R,5R,6R)-4,5-dihydroxy-6-(hydroxymethyl)piperidin-3-yl]butanamide
Template:ABSTRACT PUBMED 24009110
Function
[NAGZ_SALTY] Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides (By similarity).
About this Structure
4hzm is a 2 chain structure with sequence from Salty. Full crystallographic information is available from OCA.
See Also
Reference
- Stubbs KA, Bacik JP, Perley-Robertson GE, Whitworth GE, Gloster TM, Vocadlo DJ, Mark BL. The Development of Selective Inhibitors of NagZ: Increased Susceptibility of Gram-Negative Bacteria to beta-Lactams. Chembiochem. 2013 Oct 11;14(15):1973-81. doi: 10.1002/cbic.201300395. Epub 2013, Sep 5. PMID:24009110 doi:https://dx.doi.org/10.1002/cbic.201300395
