4jcj: Difference between revisions
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{{STRUCTURE_4jcj| PDB=4jcj | SCENE= }} | {{STRUCTURE_4jcj| PDB=4jcj | SCENE= }} | ||
===Crystal structure of Isl1 LIM domains with Ldb1 LIM-interaction domain=== | ===Crystal structure of Isl1 LIM domains with Ldb1 LIM-interaction domain=== | ||
{{ABSTRACT_PUBMED_23750000}} | |||
==Function== | ==Function== | ||
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==About this Structure== | ==About this Structure== | ||
[[4jcj]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JCJ OCA]. | [[4jcj]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JCJ OCA]. | ||
==Reference== | |||
<ref group="xtra">PMID:023750000</ref><references group="xtra"/><references/> | |||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
[[Category: Gadd, M S.]] | [[Category: Gadd, M S.]] | ||
Revision as of 05:04, 10 October 2013
Crystal structure of Isl1 LIM domains with Ldb1 LIM-interaction domain
Template:ABSTRACT PUBMED 23750000
Function
[ISL1_MOUSE] Binds and regulates the promoters of the insulin, glucagon and somatostatin genes. Involved in the specificarion of motor neurons in cooperation with LHX3 and LDB1.
About this Structure
4jcj is a 3 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.
Reference
- Gadd MS, Jacques DA, Nisevic I, Craig VJ, Kwan AH, Guss JM, Matthews JM. A structural basis for the regulation of the LIM-homeodomain protein islet 1 (Isl1) by intra- and intermolecular interactions. J Biol Chem. 2013 Jul 26;288(30):21924-35. doi: 10.1074/jbc.M113.478586. Epub, 2013 Jun 9. PMID:23750000 doi:https://dx.doi.org/10.1074/jbc.M113.478586
