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{{STRUCTURE_4jnd|  PDB=4jnd  |  SCENE=  }}
==Structure of a C.elegans sex determining protein==
===Structure of a C.elegans sex determining protein===
<StructureSection load='4jnd' size='340' side='right' caption='[[4jnd]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
 
== Structural highlights ==
==Function==
<table><tr><td colspan='2'>[[4jnd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JND OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JND FirstGlance]. <br>
[[http://www.uniprot.org/uniprot/FEM2_CAEEL FEM2_CAEEL]] Probable phosphatase involved in the regulation of sex determination. Plays an important role in regulating a pathway transducing a non-cell-autonomous signal to a nuclear transcription factor. Promotes apoptosis. Together with fem-3 associates with the CBC(fem-1) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of tra-1.  
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
 
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fem-2, T19C3.8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=6239 Caenorhabditis elegans])</td></tr>
==About this Structure==
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoprotein_phosphatase Phosphoprotein phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.16 3.1.3.16] </span></td></tr>
[[4jnd]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Caenorhabditis_elegans Caenorhabditis elegans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JND OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jnd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jnd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4jnd RCSB], [http://www.ebi.ac.uk/pdbsum/4jnd PDBsum]</span></td></tr>
</table>
__TOC__
</StructureSection>
[[Category: Caenorhabditis elegans]]
[[Category: Caenorhabditis elegans]]
[[Category: Phosphoprotein phosphatase]]
[[Category: Phosphoprotein phosphatase]]
[[Category: Feng, Y.]]
[[Category: Feng, Y]]
[[Category: Ge, J.]]
[[Category: Ge, J]]
[[Category: Yang, M.]]
[[Category: Yang, M]]
[[Category: Zhang, Y.]]
[[Category: Zhang, Y]]
[[Category: Cytosol]]
[[Category: Cytosol]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]

Revision as of 14:59, 21 December 2014

Structure of a C.elegans sex determining protein

4jnd, resolution 1.65Å

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