2hrl: Difference between revisions

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[[Image:2hrl.gif|left|200px]]<br /><applet load="2hrl" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2hrl.gif|left|200px]]
caption="2hrl, resolution 1.85&Aring;" />
 
'''Siglec-7 in complex with GT1b'''<br />
{{Structure
|PDB= 2hrl |SIZE=350|CAPTION= <scene name='initialview01'>2hrl</scene>, resolution 1.85&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene> and <scene name='pdbligand=CEQ:ETHYL-TRIMETHYL-SILANE'>CEQ</scene>
|ACTIVITY=
|GENE=
}}
 
'''Siglec-7 in complex with GT1b'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2HRL is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NAG:'>NAG</scene> and <scene name='pdbligand=CEQ:'>CEQ</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HRL OCA].  
2HRL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HRL OCA].  


==Reference==
==Reference==
Siglec-7 undergoes a major conformational change when complexed with the alpha(2,8)-disialylganglioside GT1b., Attrill H, Imamura A, Sharma RS, Kiso M, Crocker PR, van Aalten DM, J Biol Chem. 2006 Oct 27;281(43):32774-83. Epub 2006 Aug 8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16895906 16895906]
Siglec-7 undergoes a major conformational change when complexed with the alpha(2,8)-disialylganglioside GT1b., Attrill H, Imamura A, Sharma RS, Kiso M, Crocker PR, van Aalten DM, J Biol Chem. 2006 Oct 27;281(43):32774-83. Epub 2006 Aug 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16895906 16895906]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: siglec-7]]
[[Category: siglec-7]]


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