2hsd: Difference between revisions

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[[Image:2hsd.gif|left|200px]]<br /><applet load="2hsd" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2hsd.gif|left|200px]]
caption="2hsd, resolution 2.64&Aring;" />
 
'''THE REFINED THREE-DIMENSIONAL STRUCTURE OF 3ALPHA,20BETA-HYDROXYSTEROID DEHYDROGENASE AND POSSIBLE ROLES OF THE RESIDUES CONSERVED IN SHORT-CHAIN DEHYDROGENASES'''<br />
{{Structure
|PDB= 2hsd |SIZE=350|CAPTION= <scene name='initialview01'>2hsd</scene>, resolution 2.64&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/3-alpha-(or_20-beta)-hydroxysteroid_dehydrogenase 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.53 1.1.1.53]
|GENE=
}}
 
'''THE REFINED THREE-DIMENSIONAL STRUCTURE OF 3ALPHA,20BETA-HYDROXYSTEROID DEHYDROGENASE AND POSSIBLE ROLES OF THE RESIDUES CONSERVED IN SHORT-CHAIN DEHYDROGENASES'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2HSD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_exfoliatus Streptomyces exfoliatus] with <scene name='pdbligand=NAD:'>NAD</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. This structure supersedes the now removed PDB entry 1HSD. Active as [http://en.wikipedia.org/wiki/3-alpha-(or_20-beta)-hydroxysteroid_dehydrogenase 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.53 1.1.1.53] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HSD OCA].  
2HSD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_exfoliatus Streptomyces exfoliatus]. This structure supersedes the now removed PDB entry 1HSD. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HSD OCA].  


==Reference==
==Reference==
The refined three-dimensional structure of 3 alpha,20 beta-hydroxysteroid dehydrogenase and possible roles of the residues conserved in short-chain dehydrogenases., Ghosh D, Wawrzak Z, Weeks CM, Duax WL, Erman M, Structure. 1994 Jul 15;2(7):629-40. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=7922040 7922040]
The refined three-dimensional structure of 3 alpha,20 beta-hydroxysteroid dehydrogenase and possible roles of the residues conserved in short-chain dehydrogenases., Ghosh D, Wawrzak Z, Weeks CM, Duax WL, Erman M, Structure. 1994 Jul 15;2(7):629-40. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/7922040 7922040]
[[Category: 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase]]
[[Category: 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: oxidoreductase]]
[[Category: oxidoreductase]]


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