Elastase: Difference between revisions

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[[Image:1esa.png|left|200px|thumb|Crystal structure of pig elastase complex with intermediate , [[1esa]]]]
[[Image:1esa.png|left|200px|thumb|Crystal structure of pig elastase complex with intermediate , [[1esa}]]]
{{STRUCTURE_1esa|  PDB=3ba0  | SIZE=400| SCENE= |right|CAPTION= Pig elastase complex with intermediate [[1esa]] }}
{{STRUCTURE_1esa|  PDB=3ba0  | SIZE=400| SCENE= |right|CAPTION= Pig elastase complex with intermediate [[1esa]] }}


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[[Elastase]] (ELA) is a chymotrypsin-like protease which breaks down proteins.  The ELAs are numbered according to their genes.  ELA2 (or PMN-ELA) is secreted by neutrophils during inflammation. The images at the left and at the right  correspond to one representative elastase structure, ''i.e.'' the human Matrix Metalloproteinase-12 (MMP12), which is macrophage ELA ([[3ba0]]). Calcium ions are shown as green balls, zinc ions are grey balls and acetohydroxamic acid is shown as space filling object.  For additional details see [[Serine Proteases]].
[[Elastase]] (ELA) is a chymotrypsin-like protease which breaks down proteins.  The ELAs are numbered according to their genes.  ELA2 (or PMN-ELA) is secreted by neutrophils during inflammation.  For additional details see [[Serine Proteases]].


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