2ht7: Difference between revisions

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[[Image:2ht7.gif|left|200px]]<br /><applet load="2ht7" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ht7.gif|left|200px]]
caption="2ht7, resolution 2.6&Aring;" />
 
'''N8 neuraminidase in open complex with oseltamivir'''<br />
{{Structure
|PDB= 2ht7 |SIZE=350|CAPTION= <scene name='initialview01'>2ht7</scene>, resolution 2.6&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=G39:5-N-ACETYL-3-(1-ETHYLPROPYL)-1-CYCLOHEXENE-1-CARBOXYLIC ACID'>G39</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18]
|GENE=
}}
 
'''N8 neuraminidase in open complex with oseltamivir'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2HT7 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus Influenza a virus] with <scene name='pdbligand=G39:'>G39</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Exo-alpha-sialidase Exo-alpha-sialidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.18 3.2.1.18] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HT7 OCA].  
2HT7 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Influenza_a_virus Influenza a virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HT7 OCA].  


==Reference==
==Reference==
The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design., Russell RJ, Haire LF, Stevens DJ, Collins PJ, Lin YP, Blackburn GM, Hay AJ, Gamblin SJ, Skehel JJ, Nature. 2006 Sep 7;443(7107):45-9. Epub 2006 Aug 16. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16915235 16915235]
The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design., Russell RJ, Haire LF, Stevens DJ, Collins PJ, Lin YP, Blackburn GM, Hay AJ, Gamblin SJ, Skehel JJ, Nature. 2006 Sep 7;443(7107):45-9. Epub 2006 Aug 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16915235 16915235]
[[Category: Exo-alpha-sialidase]]
[[Category: Exo-alpha-sialidase]]
[[Category: Influenza a virus]]
[[Category: Influenza a virus]]
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[[Category: oseltamivir]]
[[Category: oseltamivir]]


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