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{{STRUCTURE_3tnj|  PDB=3tnj  |  SCENE=  }}
==Crystal structure of universal stress protein from Nitrosomonas europaea with AMP bound==
===Crystal structure of universal stress protein from Nitrosomonas europaea with AMP bound===
<StructureSection load='3tnj' size='340' side='right' caption='[[3tnj]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
{{ABSTRACT_PUBMED_23745136}}
== Structural highlights ==
<table><tr><td colspan='2'>[[3tnj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Nitrosomonas_europaea_atcc_19718 Nitrosomonas europaea atcc 19718]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TNJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3TNJ FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2pfs|2pfs]]</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">NE1028 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=228410 Nitrosomonas europaea ATCC 19718])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3tnj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3tnj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3tnj RCSB], [http://www.ebi.ac.uk/pdbsum/3tnj PDBsum]</span></td></tr>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
We present the crystal structures of two universal stress proteins (USP) from Archaeoglobus fulgidus and Nitrosomonas europaea in both apo- and ligand-bound forms. This work is the first complete synthesis of the structural properties of 26 USP available in the Protein Data Bank, over 75% of which were determined by structure genomics centers with no additional information provided. The results of bioinformatic analyses of all available USP structures and their sequence homologs revealed that these two new USP structures share overall structural similarity with structures of USPs previously determined. Clustering and cladogram analyses, however, show how they diverge from other members of the USP superfamily and show greater similarity to USPs from organisms inhabiting extreme environments. We compared them with other archaeal and bacterial USPs and discuss their similarities and differences in context of structure, sequential motifs, and potential function. We also attempted to group all analyzed USPs into families, so that assignment of the potential function to those with no experimental data available would be possible by extrapolation.


==About this Structure==
Structural and functional insight into the universal stress protein family.,Tkaczuk KL, A Shumilin I, Chruszcz M, Evdokimova E, Savchenko A, Minor W Evol Appl. 2013 Apr;6(3):434-49. doi: 10.1111/eva.12057. Epub 2013 Mar 13. PMID:23745136<ref>PMID:23745136</ref>
[[3tnj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Nitrosomonas_europaea_atcc_19718 Nitrosomonas europaea atcc 19718]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3TNJ OCA].


==Reference==
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
<ref group="xtra">PMID:023745136</ref><references group="xtra"/><references/>
</div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Nitrosomonas europaea atcc 19718]]
[[Category: Nitrosomonas europaea atcc 19718]]
[[Category: Chruszcz, M.]]
[[Category: Chruszcz, M]]
[[Category: Edwards, A.]]
[[Category: Edwards, A]]
[[Category: Evdokimova, E.]]
[[Category: Evdokimova, E]]
[[Category: Joachimiak, A.]]
[[Category: Joachimiak, A]]
[[Category: Kagan, O.]]
[[Category: Kagan, O]]
[[Category: MCSG, Midwest Center for Structural Genomics.]]
[[Category: Structural genomic]]
[[Category: Minor, W.]]
[[Category: Minor, W]]
[[Category: Savchenko, A.]]
[[Category: Savchenko, A]]
[[Category: Shumilin, I A.]]
[[Category: Shumilin, I A]]
[[Category: Tkaczuk, K L.]]
[[Category: Tkaczuk, K L]]
[[Category: Chaperone]]
[[Category: Chaperone]]
[[Category: Mcsg]]
[[Category: Mcsg]]
[[Category: Midwest center for structural genomic]]
[[Category: Psi-biology]]
[[Category: Psi-biology]]
[[Category: Structural genomic]]
[[Category: Universal stress protein]]
[[Category: Universal stress protein]]
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