4iqu: Difference between revisions
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{{STRUCTURE_4iqu| PDB=4iqu | SCENE= }} | |||
===Tdt core in complex with inhibitor (2Z,5E)-6-[4-(4-fluorobenzoyl)-1H-pyrrol-2-yl]-2-hydroxy-4-oxohexa-2,5-dienoic acid=== | |||
{{ABSTRACT_PUBMED_23968551}} | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/TDT_MOUSE TDT_MOUSE]] Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. One of the in vivo functions of this enzyme is the addition of nucleotides at the junction (N region) of rearranged Ig heavy chain and T-cell receptor gene segments during the maturation of B- and T-cells. | |||
==About this Structure== | |||
[[4iqu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IQU OCA]. | |||
==Reference== | |||
<ref group="xtra">PMID:023968551</ref><references group="xtra"/><references/> | |||
[[Category: DNA nucleotidylexotransferase]] | |||
[[Category: Mus musculus]] | |||
[[Category: Delarue, M.]] | |||
[[Category: Gouge, J.]] | |||
[[Category: Terminal transferase]] | |||
[[Category: Transferase-transferase inhibitor complex]] | |||