4jrt: Difference between revisions
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==Crystal structure of an A-form RNA duplex containing three GU base pairs== | |||
=== | <StructureSection load='4jrt' size='340' side='right' caption='[[4jrt]], [[Resolution|resolution]] 2.60Å' scene=''> | ||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4jrt]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4JRT OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4JRT FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4jrt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4jrt OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4jrt RCSB], [http://www.ebi.ac.uk/pdbsum/4jrt PDBsum]</span></td></tr> | |||
</table> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
In the course of a crystallographic study of a 132 nt variant of Aquifex aeolicus 6S RNA, a crystal structure of an A-form RNA duplex containing 12 base pairs was solved at a resolution of 2.6 A. In fact, the RNA duplex is part of the 6S RNA and was obtained by accidental but precise degradation of the 6S RNA in a crystallization droplet. 6S RNA degradation was confirmed by microscopic observation of crystals and gel electrophoresis of crystallization droplets. The RNA oligomers obtained form regular A-form duplexes containing three GoU wobble-type base pairs, one of which engages in intermolecular contacts through a ribose-zipper motif at the crystal-packing interface. | |||
Structure of an A-form RNA duplex obtained by degradation of 6S RNA in a crystallization droplet.,Kondo J, Dock-Bregeon AC, Willkomm DK, Hartmann RK, Westhof E Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Jun;69(Pt 6):634-9. doi:, 10.1107/S1744309113013018. Epub 2013 May 24. PMID:23722840<ref>PMID:23722840</ref> | |||
== | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | |||
[[Category: Dock-Bregeon, A C | == References == | ||
[[Category: Hartmann, R K | <references/> | ||
[[Category: Kondo, J | __TOC__ | ||
[[Category: Westhof, E | </StructureSection> | ||
[[Category: Willkomm, D K | [[Category: Dock-Bregeon, A C]] | ||
[[Category: Hartmann, R K]] | |||
[[Category: Kondo, J]] | |||
[[Category: Westhof, E]] | |||
[[Category: Willkomm, D K]] | |||
[[Category: A-form rna]] | [[Category: A-form rna]] | ||
[[Category: Gu base pair]] | [[Category: Gu base pair]] | ||
[[Category: Ribose-zipper motif]] | [[Category: Ribose-zipper motif]] | ||
[[Category: Rna]] | [[Category: Rna]] | ||
Revision as of 15:07, 21 December 2014
Crystal structure of an A-form RNA duplex containing three GU base pairs
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