2i4j: Difference between revisions

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[[Image:2i4j.gif|left|200px]]<br /><applet load="2i4j" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2i4j.gif|left|200px]]
caption="2i4j, resolution 2.100&Aring;" />
 
'''Crystal structure of the complex between PPARgamma and the agonist LT160 (ureidofibrate derivative)'''<br />
{{Structure
|PDB= 2i4j |SIZE=350|CAPTION= <scene name='initialview01'>2i4j</scene>, resolution 2.100&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=DRJ:(2R)-2-(4-{2-[1,3-BENZOXAZOL-2-YL(HEPTYL)AMINO]ETHYL}PHENOXY)-2-METHYLBUTANOIC ACID'>DRJ</scene>
|ACTIVITY=
|GENE= PPARG, NR1C3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Crystal structure of the complex between PPARgamma and the agonist LT160 (ureidofibrate derivative)'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2I4J is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=DRJ:'>DRJ</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I4J OCA].  
2I4J is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I4J OCA].  


==Reference==
==Reference==
Insights into the mechanism of partial agonism: crystal structures of the peroxisome proliferator-activated receptor gamma ligand-binding domain in the complex with two enantiomeric ligands., Pochetti G, Godio C, Mitro N, Caruso D, Galmozzi A, Scurati S, Loiodice F, Fracchiolla G, Tortorella P, Laghezza A, Lavecchia A, Novellino E, Mazza F, Crestani M, J Biol Chem. 2007 Jun 8;282(23):17314-24. Epub 2007 Apr 2. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17403688 17403688]
Insights into the mechanism of partial agonism: crystal structures of the peroxisome proliferator-activated receptor gamma ligand-binding domain in the complex with two enantiomeric ligands., Pochetti G, Godio C, Mitro N, Caruso D, Galmozzi A, Scurati S, Loiodice F, Fracchiolla G, Tortorella P, Laghezza A, Lavecchia A, Novellino E, Mazza F, Crestani M, J Biol Chem. 2007 Jun 8;282(23):17314-24. Epub 2007 Apr 2. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17403688 17403688]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: bundle of alpha-helices and a small four-stranded beta-sheet]]
[[Category: bundle of alpha-helices and a small four-stranded beta-sheet]]


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