4k2o: Difference between revisions
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{{STRUCTURE_4k2o| PDB=4k2o | SCENE= }} | |||
===The Structure of a Triple Mutant of the Tiam1 PH-CC-Ex Domain=== | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/TIAM1_HUMAN TIAM1_HUMAN]] Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA. | |||
==About this Structure== | |||
[[4k2o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K2O OCA]. | |||
[[Category: Homo sapiens]] | |||
[[Category: Fuentes, E J.]] | |||
[[Category: Gakhar, L.]] | |||
[[Category: Joshi, M.]] | |||
[[Category: Par-3]] | |||
[[Category: Ph and coiled coil domain]] | |||
[[Category: Phosphoinositide binding]] | |||
[[Category: Protein-protein interaction]] | |||
[[Category: Signaling protein]] | |||
[[Category: Tight junction]] | |||