4k2o: Difference between revisions

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'''Unreleased structure'''
{{STRUCTURE_4k2o|  PDB=4k2o  |  SCENE=  }}
===The Structure of a Triple Mutant of the Tiam1 PH-CC-Ex Domain===


The entry 4k2o is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/TIAM1_HUMAN TIAM1_HUMAN]] Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP-dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Activates RAC1, CDC42, and to a lesser extent RHOA.


Authors: Joshi, M., Gakhar, L., Fuentes, E.J.
==About this Structure==
 
[[4k2o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4K2O OCA].
Description: The Structure of a Triple Mutant of the Tiam1 PH-CC-Ex Domain
[[Category: Homo sapiens]]
[[Category: Fuentes, E J.]]
[[Category: Gakhar, L.]]
[[Category: Joshi, M.]]
[[Category: Par-3]]
[[Category: Ph and coiled coil domain]]
[[Category: Phosphoinositide binding]]
[[Category: Protein-protein interaction]]
[[Category: Signaling protein]]
[[Category: Tight junction]]