4l2x: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,330,058 edits
No edit summary
Line 1: Line 1:
'''Unreleased structure'''
{{STRUCTURE_4l2x|  PDB=4l2x  |  SCENE=  }}
===Crystal structure of human FPPS in complex with magnesium, CL02134, and inorganic pyrophosphate===
{{ABSTRACT_PUBMED_23998921}}


The entry 4l2x is ON HOLD  until Paper Publication
==Function==
[[http://www.uniprot.org/uniprot/FPPS_HUMAN FPPS_HUMAN]] Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate.


Authors: Park, J., Leung, C.-Y., Tsantrizos, Y.S., Berghuis, A.M.
==About this Structure==
[[4l2x]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4L2X OCA].  


Description: Crystal structure of human FPPS in complex with magnesium, CL02134, and inorganic pyrophosphate
==Reference==
<ref group="xtra">PMID:023998921</ref><references group="xtra"/><references/>
[[Category: Berghuis, A M.]]
[[Category: Leung, C Y.]]
[[Category: Park, J.]]
[[Category: Tsantrizos, Y S.]]
[[Category: Transferase-transferase inhibitor complex]]
Retrieved from "https://proteopedia.org/4l2x"