4lc6: Difference between revisions

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{{STRUCTURE_4lc6|  PDB=4lc6  |  SCENE=  }}
==Crystal structure of the mutant H128Q of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP==
===Crystal structure of the mutant H128Q of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP===
<StructureSection load='4lc6' size='340' side='right' caption='[[4lc6]], [[Resolution|resolution]] 1.32&Aring;' scene=''>
 
== Structural highlights ==
==Function==
<table><tr><td colspan='2'>[[4lc6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus_str._delta_h Methanothermobacter thermautotrophicus str. delta h]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LC6 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4LC6 FirstGlance]. <br>
[[http://www.uniprot.org/uniprot/PYRF_METTH PYRF_METTH]] Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).[HAMAP-Rule:MF_01200_A]
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMP:6-HYDROXYURIDINE-5-PHOSPHATE'>BMP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
 
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3ltp|3ltp]]</td></tr>
==About this Structure==
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">pyrF, MTH_129 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=187420 Methanothermobacter thermautotrophicus str. Delta H])</td></tr>
[[4lc6]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus_str._delta_h Methanothermobacter thermautotrophicus str. delta h]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LC6 OCA].  
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Orotidine-5'-phosphate_decarboxylase Orotidine-5'-phosphate decarboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.23 4.1.1.23] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4lc6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lc6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4lc6 RCSB], [http://www.ebi.ac.uk/pdbsum/4lc6 PDBsum]</span></td></tr>
</table>
__TOC__
</StructureSection>
[[Category: Methanothermobacter thermautotrophicus str. delta h]]
[[Category: Methanothermobacter thermautotrophicus str. delta h]]
[[Category: Orotidine-5'-phosphate decarboxylase]]
[[Category: Orotidine-5'-phosphate decarboxylase]]
[[Category: Almo, S C.]]
[[Category: Almo, S C]]
[[Category: Desai, B.]]
[[Category: Desai, B]]
[[Category: Fedorov, A A.]]
[[Category: Fedorov, A A]]
[[Category: Fedorov, E V.]]
[[Category: Fedorov, E V]]
[[Category: Gerlt, J A.]]
[[Category: Gerlt, J A]]
[[Category: Lyase-lyase inhibitor complex]]
[[Category: Lyase-lyase inhibitor complex]]
[[Category: Ompdc barrel]]
[[Category: Ompdc barrel]]
[[Category: Orotidine 5'-monophosphate decarboxylase]]
[[Category: Orotidine 5'-monophosphate decarboxylase]]
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