2ice: Difference between revisions

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[[Image:2ice.gif|left|200px]]<br /><applet load="2ice" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ice.gif|left|200px]]
caption="2ice, resolution 3.100&Aring;" />
 
'''CRIg bound to C3c'''<br />
{{Structure
|PDB= 2ice |SIZE=350|CAPTION= <scene name='initialview01'>2ice</scene>, resolution 3.100&Aring;
|SITE= <scene name='pdbsite=AC1:Nag+Binding+Site+For+Residue+A+643'>AC1</scene>, <scene name='pdbsite=AC2:Ca+Binding+Site+For+Residue+A+645'>AC2</scene> and <scene name='pdbsite=AC3:Ca+Binding+Site+For+Residue+D+643'>AC3</scene>
|LIGAND= <scene name='pdbligand=CA:CALCIUM ION'>CA</scene>
|ACTIVITY=
|GENE= VSIG4 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''CRIg bound to C3c'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2ICE is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Known structural/functional Sites: <scene name='pdbsite=AC1:Nag+Binding+Site+For+Residue+A+643'>AC1</scene>, <scene name='pdbsite=AC2:Ca+Binding+Site+For+Residue+A+645'>AC2</scene> and <scene name='pdbsite=AC3:Ca+Binding+Site+For+Residue+D+643'>AC3</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ICE OCA].  
2ICE is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ICE OCA].  


==Reference==
==Reference==
Structure of C3b in complex with CRIg gives insights into regulation of complement activation., Wiesmann C, Katschke KJ, Yin J, Helmy KY, Steffek M, Fairbrother WJ, McCallum SA, Embuscado L, DeForge L, Hass PE, van Lookeren Campagne M, Nature. 2006 Nov 9;444(7116):217-20. Epub 2006 Oct 15. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17051150 17051150]
Structure of C3b in complex with CRIg gives insights into regulation of complement activation., Wiesmann C, Katschke KJ, Yin J, Helmy KY, Steffek M, Fairbrother WJ, McCallum SA, Embuscado L, DeForge L, Hass PE, van Lookeren Campagne M, Nature. 2006 Nov 9;444(7116):217-20. Epub 2006 Oct 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17051150 17051150]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: immune system]]
[[Category: immune system]]


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